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REN001 for Adults with Primary Mitochondrial Myopathy
This study is no longer recruiting.
The purpose of this new clinical trial is to investigate study drug βREN001β in adult patients with Primary Mitochondrial Myopathy. REN001 is currently not approved by the U.S. Food and Drug Administration nor any other regulatory agencies for this disease; it is considered an experimental drug. The study period will last for approximately 9 months and will include at least 4 outpatient visits at CHOP, where participants will be provided the study drug or placebo and monitored for safety. The study also involves blood and urine tests, cardiac tests, physical exercise tests, and other study procedures. For more information: https://www.clinicaltrials.gov/ct2/show/NCT04535609
Participants will be able to receive travel support and reimbursement for related expenses.
Eligibility & Criteria
Visit Criteria
The study will require at least 4 outpatient visits at CHOP; procedures include:
- Medical history review; physical examinations
- Cardiac tests; eye examinations; wrist x-ray (if you are younger than 25 years)
- Physical exercise tests
- Blood and urine tests
- Study assessments; review of eDiary (including pedometer)
- Randomized to take daily study drug (REN001) or placebo