Results for iPSC

CHOP and Penn researchers find connection between mitochondrial function and mental illness in patients with a rare genetic disorder.

This week’s research news features CHOP’s participation in a study that found outcome disparities by race/ethnicity in children with severe sepsis.

Meet four women in science who are driving discovery at Children's Hospital of Philadelphia Research Institute.

From brain plasticity to medical cannabis for use in autism, don't miss this week's roundup of research headlines from CHOP.

Looking at a scientific problem from new and different perspectives is what research is all about, which is why Children's Hospital of Philadelphia's Research Institute is dedicated to cultivating a more diverse workforce. "We value diversity within our research community and it is undoubtedly part of what makes us successful," wrote Bryan A. Wolf, MD, PhD, Chief Scientific Officer and Director

Dr. Kalish recently received an award from the Alex’s Lemonade Stand Foundation to investigate tumor development associated with the rare childhood overgrowth disease Beckwith-Wiedemann Syndrome.

One in every 691 babies in the U.S. is born with Down syndrome, according to the National Down Syndrome Society, and have a predisposition for a certain kind of cancer.

The term “stem cell,” stammzellen, was first used in 1868 by the German biologist Ernst Haeckel to describe the original, unicellular progenitor from which Dr. Haekel supposed all multicellular plant and animal life might have descended.

First produced in the past decade, induced pluripotent stem cells — which are derived from adult cells — are capable of developing into many cell types. In two new studies, investigators from The Children’s Hospital of Philadelphia reprogrammed skin cells from patients with rare disorders into induced pluripotent stem cells (iPSCs), highlighting the great promise these cells hold.