Results for Ubiquitin

1 - 10 of 15

Dr. Oliver investigates the mechanisms governing T cell activation and protective immunity. Her goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

E-mail:

oliverp1 [at] chop.edu

Wei Tong, PhD

Dr. Tong investigates cytokine receptor signaling in normal and neoplastic hematopoietic development. She uses integrated approaches encompassing biochemistry, molecular biology, mouse models, and primary human samples to understand signaling events emanating from cytokine receptors that regulate the development of hematopoietic stem/progenitor cells.

E-mail:

tongw [at] chop.edu

Craig H. Bassing, PhD

Dr. Bassing's research program focuses on the genetic, epigenetic, and biochemical mechanisms by which mammals develop their immune systems while suppressing autoimmunity and genomic aberrations that cause leukemia or lymphoma.

E-mail:

bassing [at] chop.edu

Piotr K. Jung, PhD

Piotr Jung is a postdoctoral fellow in the Wolpaw Lab focused on modeling lineage heterogeneity in neuroblastoma. Jung is interested in how three-dimensional culture methods impact cell state.

E-mail:

jungpk [at] chop.edu

Meet the Co-chairs of the CHOP Postdoctoral Alliance

Published on

Sep 18, 2020

in Cornerstone Blog

The Co-chairs of the CHOP Postdoctoral Alliance reflect on the CPA’s first year and discuss plans for the second year.

Protein Network Signals Found to Drive Myeloid Leukemias

Published on

Jun 14, 2017

in Press Releases

CHOP Team’s Discovery May Advance Treatments

Putting the Brakes on Allergic Response

Published on

Apr 21, 2016

in Cornerstone Blog

When you have a chronic allergic disorder, it’s easy to blame the trigger — an early pollen season or furry pet — but the real culprit is your own immune system. Designed to attack foreign substances such as bacteria and viruses, T cells are the immune system’s watchdog to recognize serious threats. But sometimes T cells can be too zealous and set in motion a signaling cascade that can cause allergic reactions to everyday things and even attack your body’s healthy cells by mistake.

Study Aims to Reveal Novel Drivers of Allergic Disease

Published on

Sep 8, 2014

in Cornerstone Blog

Investigators at The Children’s Hospital of Philadelphia are studying the underlying biological features that could be common from one allergic disease to another.

Tong Laboratory

The Tong laboratory studies cytokine receptor and ubiquitin signaling in hematopoietic stem cells, bone marrow failure, and leukemia.

Oliver Laboratory

The Oliver Lab focuses on revealing mechanisms governing T cell activation and protective immunity. Its goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.