Dr. Ma focuses on immune engineering. He leverages genetic, chemistry, and engineering tools to dissect immune cell-cell and cell-tissue crosstalk and harness these crosstalk mechanisms to develop biomaterials, protein, and cell-based precision immunotherapies for cancer and autoimmune diseases.
A surgeon-scientist explores exosome-mediated stem cell engraftment as a means to lessen disease severity and enhance quality of life for children with hemoglobinopathies.
When the immune system inappropriately destroys blood cells, in a relatively rare group of diseases called autoimmune cytopenias, children may suffer for years with anemia, uncontrolled bleeding, and vulnerability to infections, while their parents struggle to find a diagnosis.
Your immune system is designed to protect against foreign invaders such as infections, but you may not realize that it also destroys abnormal cells that your body produces.
After 30 years of research, one surgeon is close to a breakthrough for sickle cell disease. It’s a good rule of thumb that when it comes to sick kids, the sooner a problem is identified and treated, the better the prognosis. Many of CHOP’s patients are toddlers, infants or even newborns. But one group of surgeons and researchers at CHOP works on a whole different timeline: They treat babies before they are even born.
Contributing breakthroughs in understanding the causes and consequences of kidney disease in children, and working toward developing cures for these rare and complex diseases.
The Ma Laboratory for Immune Engineering designs novel genetic, chemistry and engineering tools to dissect immune cell-cell and cell-tissue crosstalk and leverages these crosstalk mechanisms to develop biomaterials, protein, and cell-based precision immunotherapies.
