Dr. Prosser's research focuses are the development and rehabilitation of movement in children, particularly those with neurological impairments. This includes the investigation of the development of impaired movement, the study of novel motor rehabilitation interventions in children, and the interaction between the processes of neuroplasticity and neuromaturation in sensorimotor systems.
Dr. Diskin's research is focused on translational genomics in childhood cancers. Her laboratory seeks to identify the genetic basis of childhood cancers by combining quantitative computational methods with rigorous "wet-lab" experimental approaches. In parallel, she has developed, and is applying, a proteogenomic approach to identify novel immunotherapeutic targets for high-risk and relapsed pediatric malignancies.
Dr. Xanthopoulos's research focuses on the development, implementation, and adherence to medical and lifestyle interventions, including non-invasive ventilation (CPAP/BPAP), eating habits, physical activity, and sleep. She has a particular interest in the interactions among behavioral, lifestyle, psychosocial and physiologic factors as they relate to health and neurobehavioral functioning and quality of life in youth and families.
Dr. Gmuca seeks to enhance the care of children with chronic musculoskeletal pain. Her current research addresses amplified musculoskeletal pain syndrome, which is a major public health issue because of its high prevalence, related socioeconomic burden, and associated risk of opioid exposure. Dr. Gmuca’s work aims to identify innovative strategies to improve long-term treatment outcomes for this patient population.
Dr. Leff's background is in child clinical psychology, and he has broad training and expertise in intervention research, mixed methods, and in leading a range of federally funded research initiatives. His research goal is to use community-based participatory research (CBPR) to develop and validate school-based aggression and bullying intervention programs and assessment tools for urban minority youth.
Dr. Loomes' research is focused on clinical and translational studies in pediatric liver disease. She works with National Institutes of Health-funded national consortia to conduct studies investigating the etiology and treatment for rare pediatric liver diseases including biliary atresia, Alagille syndrome, and others. Dr. Loomes also collaborates with other investigators at Children’s Hospital of Philadelphia to investigate genetic causes of pediatric liver disease.