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Results for Tolerance

1 - 10 of 61

Andrew D. Wells, PhD
Andrew D. Wells

Dr. Wells studies the genetic, epigenetic, and transcriptional mechanisms that control T lymphocyte immunity and tolerance.

E-mail:
wellsa [at] chop.edu
Neil D. Romberg, MD
Neil D. Romberg

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

E-mail:
rombergn [at] chop.edu
Benjamin J. Samelson-Jones, MD, PhD
Benjamin J. Samelson-Jones

Dr. Samelson-Jones is a pediatric hematologist dedicated to improving the lives of children with bleeding and clotting disorders. His research focuses on gene therapy for hemophilia, the biochemical basis of coagulation, and the immune responses to hemophilia therapies.

E-mail:
samelsonjonesb [at] chop.edu
Leyuan Ma, PhD
Leyuan Ma

Dr. Ma focuses on immune engineering. He leverages genetic, chemistry, and engineering tools to dissect immune cell-cell and cell-tissue crosstalk and harness these crosstalk mechanisms to develop biomaterials, protein, and cell-based precision immunotherapies for cancer and autoimmune diseases.

E-mail:
mal5 [at] chop.edu
Elizabeth Lowenthal, MD, MSCE
Elizabeth Lowenthal Headshot

Dr. Lowenthal's work is focused on addressing health priorities for children in resource-limited settings. In addition to research projects she serves as research director for the Children's Hospital of Philadelphia Global Health Center, supporting junior researchers (and senior researchers newly working in international settings) to develop projects addressing other health priorities for children in resource-limited settings.

E-mail:
lowenthale [at] chop.edu
Amanda E. Bennett, MD, MPH
Amanda E. Bennett

Dr. Bennett’s research interests include screening for medical and behavioral co-morbidities in individuals with developmental disabilities, with specific interest in improving screening and outcome measures for children with autism spectrum disorder.

E-mail:
bennettam [at] chop.edu

CHOP Research Institute Scientific Symposium: Harnessing the Immune Response

Published on
Jun 2, 2022
in Cornerstone Blog
Scientific Symposium 2022: Harnessing the Immune Response
CHOP and Penn researchers discussed the latest findings about the mechanisms of immunity at the CHOP Research Institute 2022 Scientific Symposium.

Snapshot Science: Can Exendin-(9-39) Treat Congenital HI in Children?

Published on
Apr 13, 2022
in Cornerstone Blog
Can Exendin-(9-39) Treat Congenital HI in Children?
New evidence from CHOP researchers supports the use of exendin-(9-39) as an effective treatment for children with HI.

Snapshot Science: Is Positive Airway Pressure Effective for Infants With OSA?

Published on
Feb 23, 2022
in Cornerstone Blog
Is Positive Airway Pressure Effective for Infants With OSA?
A new study provides support for the use of positive airway pressure to treat OSA in infants.

CHOP Researchers Develop First Drug Treatment Approved for Severe Bone Disease

Published on
Jan 31, 2022
in Cornerstone Blog
CHOP Researchers Develop First Drug Treatment for FOP
Identified by CHOP researchers, palovarotene is the first drug approved (in Canada) for fibrodysplasia ossificans progressiva, a severe bone disease.
1 - 10 of 61

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In this section

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  • Principal Investigator / Faculty (6)

Organizations

  • Division of Endocrinology and Diabetes (7)
  • Department of Pathology and Laboratory Medicine (4)
  • Advancement of Hyperinsulinism Care and Research (3)
  • Congenital Hyperinsulinism Research Laboratory (3)
  • De León-Crutchlow Laboratory (3)
  • Department of Pediatrics (3)
  • Division of Human Genetics (3)
  • Division of Pulmonary and Sleep Medicine (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Center for Applied Genomics (2)
  • Center for Autism Research (2)
  • Center for Injury Research and Prevention (2)
  • Division of Allergy and Immunology (2)
  • Division of Neurology (2)
  • Division of Orthopaedic Surgery (2)
  • Division of Rheumatology (2)
  • Food Allergy Center (2)
  • Grant Laboratory (2)
  • Mitochondrial Medicine (2)
  • PolicyLab (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Wells Laboratory (2)
  • Ackermann Laboratory (1)
  • Blobel Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Human Phenomic Science (1)
  • CHPS Research Nursing Core (1)
  • Clinical In Vivo Gene Therapy (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • DBHi Bioinformatics (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (1)
  • Department of Surgery (1)
  • Division of Cancer Pathobiology (1)
  • Division of Hematology (1)
  • Division of Infectious Diseases (1)
  • Division of Oncology (1)
  • Division of Protective Immunity (1)
  • Immune Dysregulation Program (1)
  • Metabolism, Nutrition, and Physical Development Research Affinity Group (1)
  • Pacifici Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Translational Research Program in Pediatric Orthopaedics (1)

In this section

Filter By

  • Principal Investigator / Faculty (6)

Organizations

  • Division of Endocrinology and Diabetes (7)
  • Department of Pathology and Laboratory Medicine (4)
  • Advancement of Hyperinsulinism Care and Research (3)
  • Congenital Hyperinsulinism Research Laboratory (3)
  • De León-Crutchlow Laboratory (3)
  • Department of Pediatrics (3)
  • Division of Human Genetics (3)
  • Division of Pulmonary and Sleep Medicine (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Center for Applied Genomics (2)
  • Center for Autism Research (2)
  • Center for Injury Research and Prevention (2)
  • Division of Allergy and Immunology (2)
  • Division of Neurology (2)
  • Division of Orthopaedic Surgery (2)
  • Division of Rheumatology (2)
  • Food Allergy Center (2)
  • Grant Laboratory (2)
  • Mitochondrial Medicine (2)
  • PolicyLab (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Wells Laboratory (2)
  • Ackermann Laboratory (1)
  • Blobel Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Human Phenomic Science (1)
  • CHPS Research Nursing Core (1)
  • Clinical In Vivo Gene Therapy (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • DBHi Bioinformatics (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (1)
  • Department of Surgery (1)
  • Division of Cancer Pathobiology (1)
  • Division of Hematology (1)
  • Division of Infectious Diseases (1)
  • Division of Oncology (1)
  • Division of Protective Immunity (1)
  • Immune Dysregulation Program (1)
  • Metabolism, Nutrition, and Physical Development Research Affinity Group (1)
  • Pacifici Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
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