Dr. Tsui's research interests include clinical informatics, natural language processing, artificial intelligence and machine learning, population informatics, data science, signal processing, mobile healthcare, and large real-time clinical production systems. He's published over 100 peer-reviewed papers.
Dr. Tong investigates cytokine receptor signaling in normal and neoplastic hematopoietic development. She uses integrated approaches encompassing biochemistry, molecular biology, mouse models, and primary human samples to understand signaling events emanating from cytokine receptors that regulate the development of hematopoietic stem/progenitor cells.
Dr. Weitzman's research program aims to understand host responses to virus infection, and the cellular environment encountered and manipulated by viruses. He studies multiple viruses in an integrated experimental approach that combines biochemistry, molecular biology, genetics, and cell biology.
Dr. Grinspan's research program focuses on oligodendrocytes, cells of the central nervous system that synthesize the myelin sheath required for transmission of nervous impulses. Her research seeks to understand the signaling pathways that regulate oligodendrocyte maturation and how they are perturbed in diseases such as multiple sclerosis, HIV, and perinatal white matter injury.
Dr. Edgar has more than 25 years of experience using non-invasive imaging to study brain function and structure in psychiatric and neurological patient populations. His most recent research focuses on studying brain structure and function maturation processes.
Dr. Koyama's research focuses on Hereditary Multiple Exostoses (HME), a genetic disorder that causes the development of multiple benign tumors on the surface of the metaphyses of long bones. Based on his extensive knowledge of the normal processes of skeletal development and growth, Dr. Koyama's research aims to clarify the molecular mechanisms of HME formation and growth.
Dr. Zhou’s outstanding research interests include mitosis-coupled DNA methylation drift and inference of cell-type-specific epigenetic signals. He developed multiple computational tools for analyzing DNA methylation data and has actively contributed to cancer genomics data analysis.
Dr. Bergelson's research focuses on the interaction of viruses with their cellular receptors. His lab identified receptors for echoviruses, coxsackieviruses, and adenoviruses, and studied their structure, physiologic function, and role in virus infection and pathogenesis in animals.
He is particularly interested in the cell biology of virus entry into cells, and receptor-induced signals required for specific events in the entry process.