Results for Sickle Cell Anemia

1 - 10 of 12

Dr. Chou investigates the mechanisms of normal hematopoietic development and how these become disrupted in hematologic diseases.

E-mail:

chous [at] email.chop.edu

View Stella T. Chou's Profile

Stefano Rivella, PhD

Dr. Rivella is an expert in the pathophysiology of erythroid and iron disorders and in the generation of lentiviral vectors for the cure of hemoglobinopathies. He also investigates additional disorders such as anemia of inflammation and hemochromatosis.

E-mail:

rivellas [at] email.chop.edu

View Stefano Rivella's Profile

Timothy S. Olson, MD, PhD

Dr. Olson aims to improve diagnostics and treatment of bone marrow failure (BMF) syndromes, and to improve clinical hematopoietic stem cell transplantation (HSCT) outcomes. He conducts clinical trials of HSCT for non-malignant hematologic diseases. His laboratory explores both basic and translational research focused on genomics of BMF and the impact of BMF on hematopoietic niche function during HSCT.

E-mail:

olsont [at] email.chop.edu

View Timothy S. Olson's Profile

Gerd Blobel, MD, PhD

Dr. Blobel investigates the fundamental mechanisms involving transcription factors, chromatin regulators, and higher order chromatin. He is gearing his basic science discoveries towards genetic and epigenetic treatment modalities. In addition, Dr. Blobel is interested in mechanism of epigenetic memory.

E-mail:

blobel [at] email.chop.edu

View Gerd Blobel's Profile

Comprehensive Center for the Cure of Sickle Cell Disease and Other Red Blood Cell Disorders

Pioneering new approaches to diagnosis, care, and treatment for patients with red blood cell disorders with novel gene therapies and stem-cell-based treatments that aim to reduce symptoms and prolong life.

Chou Laboratory

The focus of the Chou Laboratory is to investigate the mechanisms of normal hematopoietic development, understand how these become disrupted in hematologic diseases, and create novel tools using induced pluripotent stem cells (iPSCs) to model blood diseases and improve treatment.

Rivella Laboratory

The Rivella Laboratory investigates erythropoiesis, iron metabolism and inflammation and develops new therapeutics for the cure of hemoglobinopathies.

Penn Medicine Awards of Excellence Honor Faculty

Published on

Oct 24, 2014

in Cornerstone Blog

The 2014 Penn Medicine Awards of Excellence recognize faculty from The Perelman School of Medicine who exemplify the highest values of innovation, commitment to service, leadership, dedication to patient care, and scholarship and teaching.

Forced Looping Viable Strategy to Reverse Globin Switch

Published on

Aug 15, 2014

in Cornerstone Blog

Investigators at The Children’s Hospital of Philadelphia are exploring a new gene therapy approach that aims to reactivate the production of fetal hemoglobin as a potential intervention for patients with sickle cell disease.

Exploring Vitamin Supplementation and Disease

Published on

Jun 13, 2014

in Cornerstone Blog

Kelly A. Dougherty, PhD recently received an award from the NIH that will support her investigation of vitamin A supplementation and sickle cell disease.