Results for Septic Shock

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Dr. Lindell’s research program is centered on the biology of critical illness in children with immune dysfunction. His current translational research is focused on pediatric septic shock and the development of multiple organ dysfunction syndrome (MODS) in critically-ill children.

E-mail:

lindellr [at] chop.edu

Leader, Mentor in Field of Pediatric Critical Care Medicine: Q&A With Robert Berg, MD

Published on

Oct 25, 2022

in Cornerstone Blog

Robert Berg, MD, receives Distinguished Career Award from American Academy of Pediatrics for his contributions to the field of resuscitation science.

Small Change May Optimize Rescue From Systemic Failure

Published on

Mar 17, 2020

in Cornerstone Blog

The PRoMPT BOLUS clinical trial will help determine the optimal fluid resuscitation to treat pediatric sepsis.

Looking Back is Forward Thinking for Sepsis Researchers

Published on

Mar 3, 2020

in Cornerstone Blog

Researchers develop surveillance algorithm to identify pediatric sepsis using routine clinical data within CHOP’s Electronic Health Records.

Researchers Use Health Data Tools to Rapidly Detect Sepsis in Sick Newborns

Published on

Mar 1, 2019

in Press Releases

Automated programs can identify which sick infants in a neonatal intensive care unit (NICU) have sepsis hours before clinicians recognize the life-threatening condition. A team of data researchers and physician-scientists tested machine-learning models in a NICU population, drawing only on routinely collected data available in electronic health records (EHRs).

In ER, Electronic Alert Helps Detect Severe Sepsis in Children

Published on

Sep 13, 2017

in Press Releases

On World Sepsis Day, CHOP Reports Improvements in Identifying a Challenging Clinical Emergency, and Launches a Multidisciplinary Pediatric Sepsis Program

PRagMatic Pediatric Trial of Balanced vs. nOrmaL Saline FlUid in Sepsis (PRoMPT BOLUS)

PRagMatic Pediatric Trial of Balanced vs. nOrmaL Saline FlUid in Sepsis (PRoMPT BOLUS) is a clinical trial to compare two commonly used treatments for pediatric sepsis to see if one is more effective and safer than the other. The treatments in this study are two different intravenous fluids: normal saline and lactated Ringer’s.

Results from the PRoMPT BOLUS Feasibility Pilot Clinical Trial

The PRoMPT BOLUS Feasibility Pilot Clinical Trial was performed between January and August 2018 to determine whether the feasibility of a multicenter, pragmatic randomized clinical trial to compare balanced (e.g., lactated Ringer’s) and 0.9% saline fluid resuscitation in children with suspected septic shock.