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Results for RNA Binding Proteins

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1 - 10 of 15

Louis R. Ghanem, MD, PhD
Louis R. Ghanem, MD, PhD

Dr. Ghanem investigates the impact of transcriptional gene expression controls and mRNA processing upon the severity and progression of pediatric inflammatory bowel disease.

E-mail:
ghaneml [at] chop.edu
Peter S. Choi, PhD
Peter S. Choi Headshot

Dr. Choi's research focuses on the role of RNA-binding proteins in the regulation of alternative splicing and how mutations in these factors contribute to cancer. He uses a combination of genetically-engineered models and high-throughput approaches to better understand how alternative splicing influences cellular function and to identify potential opportunities for therapeutic intervention.

E-mail:
choip [at] chop.edu
Kathryn E. Hamilton, PhD
Kathryn E. Hamilton

Dr. Hamilton studies intestinal epithelial cells and how they help maintain human health. Although there is a great deal understood about how these cells function, little is known about how they behave during disease. Dr. Hamilton focuses on defining new mechanisms in regenerative medicine, inflammatory bowel disease, and colorectal cancer.

E-mail:
hamiltonk1 [at] chop.edu

‘Making Sure to Share Knowledge:’ Faculty Spotlight With Peter Choi, PhD

Published on
Mar 29, 2022
in Cornerstone Blog
Q&A With Peter Choi, PhD
Dr. Choi, our Faculty Spotlight scientist for March, discusses the important role of mentorship in academia.

NIH New Innovator Award Supports Search for Answers in Splicing Codes and Cancer

Published on
Jan 13, 2022
in Cornerstone Blog
NIH Award Supports Search for Answers in Splicing Codes
Peter Choi, PhD, received the prestigious award for research into the hidden determinants of RNA splicing.

Faculty Spotlight: Q&A With Kathryn Hamilton, PhD - Elucidating Intestinal Stem Cells

Published on
Mar 12, 2021
in Cornerstone Blog
Q&A With Kathryn Hamilton PhD
Our March featured faculty member, Kathryn Hamilton, PhD, studies gastrointestinal epithelial stem cells.

Snapshot Science: How Does a New Computational Method Transform Public Big Data Into Knowledge of Transcript Splicing?

Published on
Mar 26, 2019
in Cornerstone Blog
Yi Xing
A new deep-learning model predicts the behavior of splicing regulation, helping researchers to increase their experiments’ efficiency.

New Computational Tool Harnesses Big Data and Deep Learning to Illuminate Dark Matter of the Transcriptome

Published on
Mar 26, 2019
in Press Releases
A research team at Children’s Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when copied from DNA.

New Computational Method Sheds Light on How Genetic Variants Alter RNA Processing

Published on
Mar 4, 2019
in Cornerstone Blog
Drs. Xing and Bahrami-Samani
Researchers with the Center for Computational and Genomic Medicine gain insights into genetic variants and RNA processing.

In the Gut: Therapeutic Discovery in the Microbiome

Published on
Nov 21, 2018
in Cornerstone Blog
microbiome
Scientists from the PennCHOP Microbiome Program shared new developments in knowledge of the microbiome at their Fifth Annual Symposium.
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In this section

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  • Principal Investigator / Faculty (3)

Organizations

  • Center for Computational and Genomic Medicine (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Center for Childhood Cancer Research (1)
  • Choi Laboratory (1)
  • Division of Cancer Pathobiology (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Hamilton Laboratory (1)
  • PennCHOP Microbiome Program (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)

In this section

Filter By

  • Principal Investigator / Faculty (3)

Organizations

  • Center for Computational and Genomic Medicine (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Center for Childhood Cancer Research (1)
  • Choi Laboratory (1)
  • Division of Cancer Pathobiology (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Hamilton Laboratory (1)
  • PennCHOP Microbiome Program (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
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