Results for RAS

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Dr. De Raedt researches pediatric high grade glioma development and aims to understand the involvement of crucial pathways. He investigates pathway interaction, and explores ways to develop therapies through analyzing human tumors, performing cellular studies, and developing accurate mouse models. This allows Dr. De Raedt and his team to perform novel pre-clinical studies that can lead to clinical trials.

E-mail:

deraedtt [at] chop.edu

Aime T. Franco, PhD

Dr. Franco researches the molecular basis of the differences between pediatric and adult onset thyroid cancer. She aims to understand how the tumor microenvironment impacts disease progression and response to therapy.

E-mail:

francoa1 [at] chop.edu

Elizabeth J.K. Bhoj, MD PhD

Dr. Bhoj's genetics research aims to discover new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, Dr. Bhoj focuses on three novel genes that lead to pediatric neurologic dysfunction: TBC1 domain-containing kinase, Histone 3.3 (H3F3A and H3F3B), and MAP4K4.

E-mail:

bhoje [at] chop.edu

CAR Student Alumni Stories: Jaclin Boorse, MEd

Published on

Jan 26, 2023

CAR Student Alumni Stories: Jaclin Boorse, MEd

Learn more about CAR Student Alumni, Jaclin Boorse, MEd.

Snapshot Science: Does Cabozantinib Treat Plexiform Neurofibromas in Neurofibromatosis Type 1?

Published on

Feb 26, 2021

in Cornerstone Blog

Snapshot Science: Does Cabozantinib Treat Plexiform Neurofibromas?

Data from a phase-2 study show that cabozantinib effectively treats plexiform neurofibromas in patients with neurofibromatosis type 1.

In the News: 22q, Mentoring Award, Neonatal E. coli, Gene Therapy, Siegel Award

Published on

Nov 20, 2020

in Cornerstone Blog

This week in the news: New awards for our scientists and findings for antibiotic stewardship, gene therapy, and 22q11.2 deletion syndrome.

John Maris, MD, Receives National Cancer Institute Outstanding Investigator Award

Published on

Feb 26, 2018

in Cornerstone Blog

John Maris, MD, distinguished neuroblastoma researcher at CHOP, received the the National Cancer Institute's prestigious Outstanding Investigator Award.

Researchers Pinpoint Mutations in Relapsed Neuroblastoma

Published on

Jun 30, 2015

in Cornerstone Blog

An international collaboration of researchers has identified several progressive series of mutations that occur in tumor cells responsible for aggressive subsets of neuroblastoma that relapse after chemotherapy.

De Raedt Laboratory

Research in the De Raedt Lab centers on pediatric high-grade glioma development and aims to understand the involvement of crucial pathways that drive these pediatric brain tumors.

Bhoj Laboratory

The Bhoj Lab is a genetics lab that discovers new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, the lab focuses on three novel genes that lead to pediatric neurologic dysfunction: TBCK, H3F3A/B, and MAP4K4.