Dr. Moorthy’s research focuses on liquid chromatography-tandem mass spectrometry assays for translational research. He is an expert in developing and validating analytical methods and their implementation for pediatric and adult clinical sample analysis.
Dr. Douglas has extensive laboratory experience investigating the cellular immunology of HIV/AIDS, primary immune deficiency diseases, and cellular immunopathologies. In addition, he has had significant involvement in studies related to immunological interactions.
It is scary to learn your child has neuroblastoma, a tumor of the peripheral nervous system that is the most common cancer in infants. It is scarier still when you get test results that show your child is in the half of neuroblastoma patients whose cancer is very aggressive and high-risk.
The overall goal of the Pei Lab of Cardiac Endocrinology is to understand how different organs react to energy cues and communicate with each other to maintain whole-organism homeostasis in both physiological and pathological contexts.
The Grinspan Lab focuses on oligodendrocytes, cells of the central nervous system that synthesize the myelin sheath required for transmission of nervous impulses. Failure of myelination results in motor and cognitive deficits. The lab’s studies seek to understand the signaling pathways that regulate oligodendrocyte maturation and how they are perturbed in diseases such as multiple sclerosis, HIV, and perinatal white matter injury.
The Oliver Lab focuses on revealing mechanisms governing T cell activation and protective immunity. Its goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma. The Oliver Lab has discovered several enzymes of the ubiquitin pathway that prevent autoimmune disease or, in other cases, prevent asthma, atopic dermatitis, or eosinophilic gastrointestinal disorders.
The Moorthy Lab focuses on liquid chromatography-tandem mass spectrometry assays for translational research. The lab evaluates and uses new tools and microsampling technologies to facilitate preclinical, translational, and clinical research.