Dr. Silber is the director of the Center for Outcomes Research at CHOP, and is an internationally known authority on outcomes measurement and severity adjustment for both adult and pediatric applications.
Dr. O'Byrne is a pediatric cardiologist with research interests in cardiac disease outcomes, perioperative outcomes, and children with pulmonary hypertension. He combines the use of large observational datasets to study outcomes, practice variation, cost, and the determinants of health-related quality of life in this population.
Dr. DeMauro has special expertise in rigorous assessment of early childhood outcomes of high-risk neonates. Her research focuses on improving outcomes of children with bronchopulmonary dysplasia and school-age assessment of functional outcomes in preterm-born children.
Dr. Walter's research in the pediatric cardiac intensive care unit includes the customization of an interprofessional team and family-based intervention to improve communication about goals of care, and teamwork and evaluation of the intervention. Knowledge gained from this research will guide future interventions to improve outcomes for pediatric patients with advanced heart disease and their families.
Dr. Forrest's research focuses on developing novel ways of conducting multi-center pediatric applied clinical research, child health services and outcomes research, pediatric person-reported outcome measure development and application, life course health science, learning health systems science, and policies and programs that promote the lifelong health of children. He has a particular interest in the concept and measurement of health.
Dr. Joffe's research addresses three areas. First, he studies leadership in biomedical science, including governance within learning healthcare systems and the role of the principal investigator in multicenter trials. Second, he studies the ethical questions raised by genomic sequencing in medicine and science. Finally, he studies the ethics of human subjects research, including informed consent and clinical research design.
Dr. Winston is a pediatrician, engineer, and public health researcher conducting research at the interface of child and adolescent health, injury, engineering, and behavioral science. Her work focuses on traffic injury, and her research to action to impact approach has led to evidence-based digital health to improve health outcomes.
Dr. Laskin's research focuses on the conduct of clinical investigations and translational studies designed to target mechanisms to prevent, treat, or slow the progression of chronic kidney disease in immunosuppressed patients, including children receiving a bone marrow or kidney transplant.
Dr. Olson aims to improve diagnostics and treatment of bone marrow failure (BMF) syndromes, and to improve clinical hematopoietic stem cell transplantation (HSCT) outcomes. He conducts clinical trials of HSCT for non-malignant hematologic diseases. His laboratory explores both basic and translational research focused on genomics of BMF and the impact of BMF on hematopoietic niche function during HSCT.
Dr. Stricker is a clinical outcomes researcher who leads the Pedi-INQUIRE perioperative research team at CHOP. He is a Leonard Davis Institute Senior Fellow, he founded the multicenter Pediatric Craniofacial Collaborative Group, and leads the international Pediatric Perioperative Outcomes Group.