PRagMatic Pediatric Trial of Balanced vs. nOrmaL Saline FlUid in Sepsis (PRoMPT BOLUS) is a clinical trial to compare two commonly used treatments for pediatric sepsis to see if one is more effective and safer than the other. The treatments in this study are two different intravenous fluids: normal saline and lactated Ringer’s.
The PRoMPT BOLUS Feasibility Pilot Clinical Trial was performed between January and August 2018 to determine whether the feasibility of a multicenter, pragmatic randomized clinical trial to compare balanced (e.g., lactated Ringer’s) and 0.9% saline fluid resuscitation in children with suspected septic shock.
