Dr. Alexander-Bloch investigates normal brain development and the altered developmental trajectories that lead to mental illness. His multi-disciplinary research integrates brain imaging, genomics and clinical information.
Dr. Zorc's work focuses on the intersection of interventional clinical research, quality improvement (QI), and clinical informatics. He has formal certification in epidemiology, QI methodology, and clinical informatics, and has participated in multi-center research networks, guideline and improvement collaboratives, and electronic health record development locally and nationally.
Dr. Huang works on methodology development to understand the dynamics of disease activities and inform health management using multivariate longitudinal health data. She also works on data integration in Clinical Research Networks.
Dr. Tan studies transcriptional regulation during normal development and disease. This involves the interplay of multiple transcription and epigenetic factors in a 3D chromosomal environment. Using experimental genomics and computational modeling, Dr. Tan investigates transcriptional regulatory networks underlying embryonic hematopoiesis, T cell differentiation, and pediatric leukemia.
Dr. Bonafide’s research focus is on developing, evaluating, and implementing interventions at the intersection of patient safety and technological innovation, and measuring the impacts of these interventions on children and families. His research includes methods drawn from clinical epidemiology, biostatistics, clinical informatics, systems engineering, and implementation science.
Dr. Maris investigates the molecular and genetic mechanisms contributing to the development and progression of neuroblastoma, a common childhood cancer. He also aims to develop new molecular diagnostic tests and less toxic, targeted therapies to treat relapsed or refractory neuroblastoma, including a major effort in immunotherapy discovery and development.
Dr. Forrest's research focuses on developing novel ways of conducting multi-center pediatric applied clinical research, child health services and outcomes research, pediatric person-reported outcome measure development and application, life course health science, learning health systems science, and policies and programs that promote the lifelong health of children. He has a particular interest in the concept and measurement of health.
Using translational approaches that encompass genomic studies, biomarker development, disease modeling, natural history studies, and clinical trials, Dr. Vanderver seeks to improve the quality of life and lifespan of individuals living with leukodystrophies or heritable disorder of myelin. She leads the Leukodystrophy Center of Excellence at Children's Hospital of Philadelphia.
Dr. Feudtner's research strives to advance the well-being of pediatric patients with complex chronic conditions and serious, often rare, illnesses, and to promote the well-being of their families. Along with his colleagues, Dr. Feudtner is conducting studies focusing on pediatric palliative care, complex care, the impact on families of pediatric serious illness, and pediatric medical ethics.
Dr. Bell, chief of the Division of General Pediatrics, has research expertise in areas including computerized clinical decision support to improve the quality of care; epidemiology, management and treatment of common pediatric infectious diseases; the use of primary care practice-based research networks for clinical research; and quality improvement through the use of clinical pathways.