Dr. Bassiri studies the ways in which the immunometabolic features of lymphocytes are altered within solid tumor environments, and how modulating these features may enhance anti-tumor immunity.
Dr. Sgourakis’ research focuses on understanding the intricate molecular mechanisms that determine the vast repertoire of peptide antigens displayed by the proteins of the Major Histocompatibility Complex for immune surveillance by T cells and Natural Killer cells.
The Bassiri Lab studies the ways in which the immunometabolic features of lymphocytes are altered within solid tumor environments, and how modulating these features may enhance anti-tumor immunity.
The Mechanistic Molecular Immunology Lab integrates cutting-edge structural biology and biochemistry tools with functional immunoassays to understand the molecular basis of immune responses to viral infections and tumors, with an emphasis on the development of novel protein-based therapeutics.
