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Results for Mitochondrial Function and Metabolic Disease

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1 - 10 of 46

Itzhak Nissim, PhD

Dr. Nissim is a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and nuclear magnetic resonance to study metabolome and fluxome and their coupling to genome in normal and disease states. His long-standing interest focuses on understanding the cause, mechanisms, and outcome of metabolic disorders.

E-mail:
nissim [at] chop.edu
Liming Pei, PhD
Liming Pei

Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.

E-mail:
peil [at] chop.edu
Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
Daniel P. Kelly, MD
Daniel P. Kelly

Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.

E-mail:
dankelly [at] pennmedicine.upenn.edu

CHOP Research Poster Day and Scientific Symposium: Making the Microbiome Less Mysterious

Published on
May 15, 2023
in Cornerstone Blog
Making the Microbiome Less Mysterious
This year’s Poster Day and Scientific Symposium featured all manners of bugs, breakthroughs, and big discoveries.

Tableside Chat About Mitochondria Leads to Gates Foundation Grant for COVID-19 Research

Published on
Mar 2, 2023
in Cornerstone Blog
Tableside Chat Leads to Gates Foundation Grant for CHOP
With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.

Understanding Mitochondrial Adaptation: Q&A With Diversity Fellow Arnold Olali, PhD

Published on
Dec 27, 2022
in Cornerstone Blog
Q&A With Diversity Fellow Arnold Olali, PhD
Featured Diversity Fellow Arnold Olali, PhD, is focused on understanding how mitochondria affect overall health.

Researchers Aim to Develop Noninvasive Methods to Diagnose Mitochondrial Diseases

Published on
Nov 9, 2022
in Cornerstone Blog
Researchers Study Diagnostic Methods for Mitochondrial Diseases
A U.S. Department of Defense grant will support CHOP researchers in their study of noninvasive methods to diagnose mitochondrial diseases.

‘The future of research benefits from diversity:’ Faculty Spotlight With Liming Pei, PhD

Published on
Oct 31, 2022
in Cornerstone Blog
Faculty Spotlight With Liming Pei, PhD
Liming Pei, PhD, studies how different organs react to energy cues and communicate with each other.

In the News: Mitochondrial Disease, ALL, Type 2 Diabetes, Sleep Apnea

Published on
Sep 16, 2022
in Cornerstone Blog
In the News
This week’s In the News highlights research on mitochondrial disease, acute lymphoblastic leukemia, type 2 diabetes, and sleep apnea.
1 - 10 of 46

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In this section

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  • Principal Investigator / Faculty (4)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (18)
  • Mitochondrial Medicine (11)
  • Department of Pathology and Laboratory Medicine (7)
  • Center for Injury Research and Prevention (4)
  • Department of Pediatrics (4)
  • Center for Applied Genomics (3)
  • Department of Anesthesiology and Critical Care Medicine (3)
  • Division of Infectious Diseases (3)
  • Wallace Laboratory (3)
  • Center for Childhood Cancer Research (2)
  • Center for Spatial and Functional Genomics (2)
  • Division of Protective Immunity (2)
  • Friedreich’s Ataxia Center of Excellence (2)
  • Inflammatory Bowel Disease Center (2)
  • Minds Matter Concussion Program (2)
  • Office of Academic Training and Outreach Programs (2)
  • PolicyLab (2)
  • CHOP Microbiome Center (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Biomedical and Health Informatics (1)
  • Division of Allergy and Immunology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Hematology (1)
  • Division of Human Genetics (1)
  • Division of Neonatology (1)
  • Division of Nephrology (1)
  • Division of Neurology (1)
  • Division of Oncology (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Division of Rheumatology (1)
  • Hamilton Laboratory (1)
  • Pei Laboratory (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (1)
  • Romberg Laboratory (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)

In this section

Filter By

  • Principal Investigator / Faculty (4)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (18)
  • Mitochondrial Medicine (11)
  • Department of Pathology and Laboratory Medicine (7)
  • Center for Injury Research and Prevention (4)
  • Department of Pediatrics (4)
  • Center for Applied Genomics (3)
  • Department of Anesthesiology and Critical Care Medicine (3)
  • Division of Infectious Diseases (3)
  • Wallace Laboratory (3)
  • Center for Childhood Cancer Research (2)
  • Center for Spatial and Functional Genomics (2)
  • Division of Protective Immunity (2)
  • Friedreich’s Ataxia Center of Excellence (2)
  • Inflammatory Bowel Disease Center (2)
  • Minds Matter Concussion Program (2)
  • Office of Academic Training and Outreach Programs (2)
  • PolicyLab (2)
  • CHOP Microbiome Center (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Biomedical and Health Informatics (1)
  • Division of Allergy and Immunology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Hematology (1)
  • Division of Human Genetics (1)
  • Division of Neonatology (1)
  • Division of Nephrology (1)
  • Division of Neurology (1)
  • Division of Oncology (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Division of Rheumatology (1)
  • Hamilton Laboratory (1)
  • Pei Laboratory (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (1)
  • Romberg Laboratory (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)
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