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Results for Mitochondrial Function and Metabolic Disease

1 - 10 of 38

Itzhak Nissim, PhD

Dr. Nissim is a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and nuclear magnetic resonance to study metabolome and fluxome and their coupling to genome in normal and disease states. His long-standing interest focuses on understanding the cause, mechanisms, and outcome of metabolic disorders.

E-mail:
nissim [at] chop.edu
Liming Pei, PhD
Liming Pei

Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.

E-mail:
peil [at] chop.edu
Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
Daniel P. Kelly, MD
Daniel P. Kelly

Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.

E-mail:
dankelly [at] pennmedicine.upenn.edu

In the News: APS Award, Exercise and Mitochondrial Disease, CHOP CVI, Driving Safety, Pandemic Stress

Published on
Apr 29, 2022
in Cornerstone Blog
Read about the latest discoveries and awards at Children’s Hospital of Philadelphia Research Institute.

In the News: Type 1 Diabetes, CZI Grant, Cystic Fibrosis, Mitochondrial Disease

Published on
Sep 3, 2021
in Cornerstone Blog
In the News: Diabetes, CZI Grant, Cystic Fibrosis, Mitochondrial Disease
This week’s In the News highlights two new studies, a new grant, the new director of the Cystic Fibrosis Center, and a physician’s new role.

Preclinical Study Shows Combination of Vitamins, Supplements May Benefit Mitochondrial Disease

Published on
Mar 26, 2021
in Cornerstone Blog
Trio of Supplements May Be Effective in Mitochondrial Disease
A combination of vitamins and supplements appears to be beneficial in treating mitochondrial disease, which has no approved treatment.

In the News: COVID Testing, Immunometabolism, Autistic Drivers, Neighborhoods and Sleep

Published on
Feb 5, 2021
in Cornerstone Blog
In the News
Discover new findings about COVID-19 testing before surgery, the link between mitochondria and autism, and how neighborhoods affect sleep.

Out of This World: CHOP Researchers Help Elucidate Health Effects of Spaceflight

Published on
Nov 25, 2020
in Cornerstone Blog
Out of This World: CHOP Researchers Help Elucidate Health Effects of Spaceflight
Researchers at CHOP collaborated with NASA and other institutions to determine possible mechanisms behind the health effects of spaceflight.

In The News: Football Concussions, Early Intervention Referrals, Mitochondrial DNA, Panama TV, ‘Research in Motion,’ Bone Marrow Failure

Published on
Oct 23, 2020
in Cornerstone Blog
In the News
This week’s roundup features research reinforcing the need for better universal surveillance for developmental delays and increased access to early intervention. This and more In The News.
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In this section

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  • Principal Investigator / Faculty (4)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (14)
  • Mitochondrial Medicine (9)
  • Center for Injury Research and Prevention (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Center for Applied Genomics (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Department of Pediatrics (2)
  • Friedreich’s Ataxia Center of Excellence (2)
  • PolicyLab (2)
  • Center for Childhood Cancer Research (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Child and Adolescent Psychiatry (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Human Genetics (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Hamilton Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Wallace Laboratory (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)

In this section

Filter By

  • Principal Investigator / Faculty (4)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (14)
  • Mitochondrial Medicine (9)
  • Center for Injury Research and Prevention (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Center for Applied Genomics (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Department of Pediatrics (2)
  • Friedreich’s Ataxia Center of Excellence (2)
  • PolicyLab (2)
  • Center for Childhood Cancer Research (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Child and Adolescent Psychiatry (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Human Genetics (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Hamilton Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Wallace Laboratory (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)
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