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Results for Mitochondrial Function

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1 - 10 of 95

Xilma R. Ortiz-Gonzalez, MD, PhD
Xilma R. Ortiz-Gonzalez

Dr. Ortiz-Gonzalez is a physician-scientist specializing in pediatric neurogenetics. Her clinical work focuses on finding a unifying genetic diagnosis for children with rare neurodevelopmental disorders. Her research is informed by her patients and focuses on understanding how genetic changes, in particular those affecting mitochondrial function, cause disease so we can develop better treatments for these children in the future.

Liming Pei, PhD
Liming Pei

Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.

E-mail:
peil [at] chop.edu
Stephen R. Master, MD, PhD
Stephen R. Master

Dr. Master works to understand the biochemical pathways related to inborn errors of metabolism, particularly as they relate to mitochondrial function. He also focuses on bioinformatics and machine learning solutions to problems in mass spectrometry and laboratory medicine.

E-mail:
masters [at] chop.edu
Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
Daniel P. Kelly, MD
Daniel P. Kelly

Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.

E-mail:
dankelly [at] pennmedicine.upenn.edu
Itzhak Nissim, PhD

Dr. Nissim is a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and nuclear magnetic resonance to study metabolome and fluxome and their coupling to genome in normal and disease states. His long-standing interest focuses on understanding the cause, mechanisms, and outcome of metabolic disorders.

E-mail:
nissim [at] chop.edu

Tableside Chat About Mitochondria Leads to Gates Foundation Grant for COVID-19 Research

Published on
Mar 2, 2023
in Cornerstone Blog
Tableside Chat Leads to Gates Foundation Grant for CHOP
With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.

In the News: Foundational Gift, Gates Grant, Community-engaged Research

Published on
Feb 17, 2023
in Cornerstone Blog
In the News: Foundational Gift, Community Partnerships
In this news roundup, learn how CHOP researchers are advancing research for neurological diseases and engaging in community collaborative research.

Understanding Mitochondrial Adaptation: Q&A With Diversity Fellow Arnold Olali, PhD

Published on
Dec 27, 2022
in Cornerstone Blog
Q&A With Diversity Fellow Arnold Olali, PhD
Featured Diversity Fellow Arnold Olali, PhD, is focused on understanding how mitochondria affect overall health.

In the News: Dr. Susan Furth, Clinical Vector Core, Mito Model, Immunotherapy

Published on
Nov 11, 2022
in Cornerstone Blog
In the News
This week’s research news roundup includes accolades for our scientists and the spaces they work in.
1 - 10 of 95

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In this section

Filter By

  • Principal Investigator / Faculty (6)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (27)
  • Mitochondrial Medicine (17)
  • Center for Injury Research and Prevention (10)
  • PolicyLab (10)
  • Department of Pediatrics (9)
  • Center for Autism Research (7)
  • Center for Applied Genomics (6)
  • Department of Pathology and Laboratory Medicine (6)
  • Anderson Laboratory (5)
  • Division of Neurology (5)
  • Department of Anesthesiology and Critical Care Medicine (4)
  • Department of Biomedical and Health Informatics (4)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (4)
  • Division of Infectious Diseases (4)
  • Division of Oncology (4)
  • Lifespan Brain Institute (4)
  • Center for Childhood Cancer Research (3)
  • Department of Radiology (3)
  • Division of Endocrinology and Diabetes (3)
  • Division of Human Genetics (3)
  • Division of Rheumatology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • Office of Academic Training and Outreach Programs (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Wallace Laboratory (3)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Spatial and Functional Genomics (2)
  • Clinical Futures (2)
  • Congenital Hyperinsulinism Research Laboratory (2)
  • Division of Adolescent Medicine (2)
  • Division of Allergy and Immunology (2)
  • Division of Gastroenterology, Hepatology, and Nutrition (2)
  • Division of Nephrology (2)
  • Minds Matter Concussion Program (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Aquatic Zebrafish Core (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • CHOP Cardiovascular Institute (1)
  • Clinical Vector Core (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • DBHi Bioinformatics (1)
  • Division of Cancer Pathobiology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Emergency Medicine (1)
  • Division of Hematology (1)
  • Division of Neonatology (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Protective Immunity (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Feudtner Laboratory (1)
  • Hamilton Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Intellectual and Developmental Disabilities Research Center (1)
  • Lurie Family Foundations MEG Imaging Center (1)
  • Mitochondria Research Affinity Group (1)
  • Pei Laboratory (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Romberg Laboratory (1)
  • The Resuscitation Science Center (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)

In this section

Filter By

  • Principal Investigator / Faculty (6)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (27)
  • Mitochondrial Medicine (17)
  • Center for Injury Research and Prevention (10)
  • PolicyLab (10)
  • Department of Pediatrics (9)
  • Center for Autism Research (7)
  • Center for Applied Genomics (6)
  • Department of Pathology and Laboratory Medicine (6)
  • Anderson Laboratory (5)
  • Division of Neurology (5)
  • Department of Anesthesiology and Critical Care Medicine (4)
  • Department of Biomedical and Health Informatics (4)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (4)
  • Division of Infectious Diseases (4)
  • Division of Oncology (4)
  • Lifespan Brain Institute (4)
  • Center for Childhood Cancer Research (3)
  • Department of Radiology (3)
  • Division of Endocrinology and Diabetes (3)
  • Division of Human Genetics (3)
  • Division of Rheumatology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • Office of Academic Training and Outreach Programs (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Wallace Laboratory (3)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Spatial and Functional Genomics (2)
  • Clinical Futures (2)
  • Congenital Hyperinsulinism Research Laboratory (2)
  • Division of Adolescent Medicine (2)
  • Division of Allergy and Immunology (2)
  • Division of Gastroenterology, Hepatology, and Nutrition (2)
  • Division of Nephrology (2)
  • Minds Matter Concussion Program (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Aquatic Zebrafish Core (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • CHOP Cardiovascular Institute (1)
  • Clinical Vector Core (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • DBHi Bioinformatics (1)
  • Division of Cancer Pathobiology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Emergency Medicine (1)
  • Division of Hematology (1)
  • Division of Neonatology (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Protective Immunity (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Feudtner Laboratory (1)
  • Hamilton Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Intellectual and Developmental Disabilities Research Center (1)
  • Lurie Family Foundations MEG Imaging Center (1)
  • Mitochondria Research Affinity Group (1)
  • Pei Laboratory (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Romberg Laboratory (1)
  • The Resuscitation Science Center (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)
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