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Results for Mitochondria

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Douglas C. Wallace, PhD
Douglas C. Wallace

Dr. Wallace is a geneticist and evolutionary biologist who founded the field of mitochondrial medicine 40 years ago. He investigates the role of mitochondria in human evolution, health, and disease.

E-mail:
wallaced1 [at] chop.edu
Marni J. Falk, MD
Marni J. Falk

Dr. Falk is a Clinical Geneticist who serves as executive director of the Mitochondrial Medicine Frontier Program. Her translational research lab investigates the causes and global metabolic consequences of mitochondrial disease, as well as targeted therapies, in C. elegans, zebrafish, mouse, and human tissue models of genetic-based respiratory chain dysfunction.

E-mail:
falkm [at] chop.edu
Michael B. Robinson, PhD
Michael B. Robinson

Dr. Robinson has a longstanding research interest in the function and regulation of brain glutamate transport under physiologic and pathologic conditions.

E-mail:
robinson [at] pennmedicine.upenn.edu
Stewart A. Anderson, MD
Stewart A. Anderson

Dr. Anderson’s research interests focus on the molecular and cellular mechanisms that govern the development of the mammalian forebrain. In his research on the development of the cerebral cortex, he is particularly interested in understanding the molecular underpinnings behind the fate determination and axon targeting of subclasses of GABAergic interneurons implicated in the neuropathology of schizophrenia.

E-mail:
andersons3 [at] chop.edu
Rebecca A. Simmons, MD
Rebecca A. Simmons

The principal goal of Dr. Simmons' research program is to elucidate the underlying molecular mechanisms that link an aberrant intrauterine milieu to the later development of diseases in adulthood. She has made many seminal contributions to the understanding of the role that epigenetic modifications play in developmental programming of obesity and type 2 diabetes.

E-mail:
simmonsr [at] chop.edu
Harry Ischiropoulos, PhD
Haralambos Ischiropoulos

Dr. Ischiropoulos's research objectives are to develop and test novel therapeutics for long-chain fatty acid oxidation (LCFA) disorders, a collection of inherited metabolic diseases that affect the heart, liver and muscle. A second area of interest is the resolution of the nitric oxide signaling pathways at the proteome level in the cardiovascular and neuronal systems.

E-mail:
ischirop [at] pennmedicine.upenn.edu
Ryan W. Morgan, MD, MTR
Ryan W. Morgan

Dr. Morgan is a resuscitation scientist who studies pediatric cardiac arrest and cardiopulmonary resuscitation (CPR) through both translational laboratory work and clinical studies. His focus is to identify disease-specific pathophysiology that can be specifically targeted during CPR.

E-mail:
morganr1 [at] chop.edu
Robert Sutton MD, MSCE, FAAP, FCCM
Robert M. Sutton

Dr. Sutton is an internationally recognized expert in pediatric cardiac arrest. His career focus is on developing and evaluating novel techniques and devices to improve the care delivered during in-hospital resuscitation attempts.

E-mail:
suttonr [at] chop.edu

In the News: FDA Approval, Opioid-related Poisoning, Science Slam, PCORI Funding

Published on
Mar 17, 2023
in Cornerstone Blog
In the News: FDA Approval, Opioid-related Poisoning
Learn about a first-of-its-kind FDA approval and a PCORI project that aims to turn evidence-based research into clinical practice more quickly.

Tableside Chat About Mitochondria Leads to Gates Foundation Grant for COVID-19 Research

Published on
Mar 2, 2023
in Cornerstone Blog
Tableside Chat Leads to Gates Foundation Grant for CHOP
With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.
1 - 10 of 95

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In this section

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  • Principal Investigator / Faculty (8)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (34)
  • Mitochondrial Medicine (17)
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  • Department of Pediatrics (9)
  • PolicyLab (6)
  • Department of Anesthesiology and Critical Care Medicine (5)
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  • Department of Pathology and Laboratory Medicine (4)
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  • Anderson Laboratory (3)
  • Center for Applied Genomics (3)
  • Center for Data-Driven Discovery in Biomedicine (3)
  • Division of Hematology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • Mitochondria Research Affinity Group (3)
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  • Center for Childhood Cancer Research (2)
  • Division of Adolescent Medicine (2)
  • Division of Endocrinology and Diabetes (2)
  • Division of Infectious Diseases (2)
  • Division of Neonatology (2)
  • Division of Oncology (2)
  • Minds Matter Concussion Program (2)
  • Office of Academic Training and Outreach Programs (2)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (2)
  • Biomedical Optical Devices to Monitor Cerebral Health (1)
  • Children’s Oncology Group (1)
  • Department of Surgery (1)
  • Division of Allergy and Immunology (1)
  • Division of General Pediatrics (1)
  • Division of Nephrology (1)
  • Division of Orthopaedic Surgery (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Hamilton Laboratory (1)
  • Hogarty Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Lifespan Brain Institute (1)
  • PEDSnet (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Research Creative Services (1)
  • Sleep Center (1)
  • The Resuscitation Science Center (1)

In this section

Filter By

  • Principal Investigator / Faculty (8)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (34)
  • Mitochondrial Medicine (17)
  • Center for Injury Research and Prevention (9)
  • Department of Pediatrics (9)
  • PolicyLab (6)
  • Department of Anesthesiology and Critical Care Medicine (5)
  • Division of Neurology (5)
  • Center for Autism Research (4)
  • Clinical Futures (4)
  • Department of Biomedical and Health Informatics (4)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (4)
  • Department of Pathology and Laboratory Medicine (4)
  • Division of Human Genetics (4)
  • Anderson Laboratory (3)
  • Center for Applied Genomics (3)
  • Center for Data-Driven Discovery in Biomedicine (3)
  • Division of Hematology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • Mitochondria Research Affinity Group (3)
  • Wallace Laboratory (3)
  • Center for Childhood Cancer Research (2)
  • Division of Adolescent Medicine (2)
  • Division of Endocrinology and Diabetes (2)
  • Division of Infectious Diseases (2)
  • Division of Neonatology (2)
  • Division of Oncology (2)
  • Minds Matter Concussion Program (2)
  • Office of Academic Training and Outreach Programs (2)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (2)
  • Biomedical Optical Devices to Monitor Cerebral Health (1)
  • Children’s Oncology Group (1)
  • Department of Surgery (1)
  • Division of Allergy and Immunology (1)
  • Division of General Pediatrics (1)
  • Division of Nephrology (1)
  • Division of Orthopaedic Surgery (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Hamilton Laboratory (1)
  • Hogarty Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Lifespan Brain Institute (1)
  • PEDSnet (1)
  • Penn-CHOP Kidney Innovation Center (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Research Creative Services (1)
  • Sleep Center (1)
  • The Resuscitation Science Center (1)
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