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Results for Islet Biology

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Amanda M. Ackermann, MD, PhD
Amanda M. Ackermann

Dr. Ackermann studies diabetes (types 1 and 2) and congenital hyperinsulinism using mouse models, cell lines, and primary human tissue. She aims to identify novel pathways regulating beta cell insulin secretion, leading to innovative therapeutic strategies for these disorders. Current studies include in vivo mouse physiology, ex vivo human islet physiology, CRISPR-Cas9 gene editing, epigenetic modification, and single-cell functional genomics.

E-mail:
ackermanna [at] chop.edu

Congenital Hyperinsulinism Research Laboratory

Congenital Hyperinsulinism Research Lab

The Congenital Hyperinsulinism Research Lab investigates genotype-phenotype correlations for genetic causes of hyperinsulinism in order to improve diagnosis and management. 

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