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Results for Human Embryonic Stem Cells

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1 - 10 of 16

Paul Gadue, PhD
Paul Gadue

Dr. Gadue studies cell fate decisions, focusing on endoderm and mesoderm specification using human embryonic stem (ES) cells and induced pluripotent stem (iPS).

E-mail:
gaduep [at] chop.edu
Kai Tan, PhD
Kai Tan

Dr. Tan studies transcriptional regulation during normal development and disease. This involves the interplay of multiple transcription and epigenetic factors in a 3D chromosomal environment. Using experimental genomics and computational modeling, Dr. Tan investigates transcriptional regulatory networks underlying embryonic hematopoiesis, T cell differentiation, and pediatric leukemia.

E-mail:
tank1 [at] chop.edu
Ethan M. Goldberg, MD, PhD
Ethan M. Goldberg

Dr. Goldberg's research program focuses on investigating cerebral cortical circuit function and dysfunction in neurodevelopmental disorders. Using a variety of research techniques, Dr. Goldberg has a specific research interest in the workings of neuron subtype called GABAergic inhibitory interneuron and the role of interneuron dysfunction in disease.

E-mail:
goldberge [at] chop.edu
Stewart A. Anderson, MD
Stewart A. Anderson

Dr. Anderson’s research interests focus on the molecular and cellular mechanisms that govern the development of the mammalian forebrain. In his research on the development of the cerebral cortex, he is particularly interested in understanding the molecular underpinnings behind the fate determination and axon targeting of subclasses of GABAergic interneurons implicated in the neuropathology of schizophrenia.

E-mail:
andersons3 [at] chop.edu
Eric Chien-Wei Liao, MD, PhD
Eric Chien-Wei Liao, MD, PhD

Dr. Liao is a pediatric plastic surgeon-scientist and the founding director of the Center for Craniofacial Innovation at Children's Hospital of Philadelphia. His research leverages convergent advances in fetal care, human genetics, and developmental biology to initiate first-in-child trials and treatments.

E-mail:
liaoce [at] chop.edu

Science Stands Out in Our Most Engaging Cornerstone Stories of 2022

Published on
Dec 29, 2022
in Cornerstone Blog
Science Stands Out in Our Most Engaging Cornerstone Stories of 2022
These six Cornerstone stories garnered the most engagements from our CHOP Research Twitter, Facebook, and LinkedIn channels.

Snapshot Science: Does In Utero BPA Exposure Affect Genes Related to Development of Diabetes and Obesity in Amniocytes?

Published on
Feb 21, 2020
in Cornerstone Blog
BPA in Pregnancy
Exposure to BPA in utero during critical periods of fetal development linked to obesity and diabetes.

Forced Looping Viable Strategy to Reverse Globin Switch

Published on
Aug 15, 2014
in Cornerstone Blog
Investigators at The Children’s Hospital of Philadelphia are exploring a new gene therapy approach that aims to reactivate the production of fetal hemoglobin as a potential intervention for patients with sickle cell disease.

Treating the Chicken with the Egg

Published on
Jan 28, 2014
in Cornerstone Blog
The term “stem cell,” stammzellen, was first used in 1868 by the German biologist Ernst Haeckel to describe the original, unicellular progenitor from which Dr. Haekel supposed all multicellular plant and animal life might have descended.

Turning Stem Cells into Brain Cells Sheds Light on Neural Development

Published on
May 15, 2013
in Cornerstone Blog
Stem cells have the unique ability to develop, or differentiate, into other kinds of cells in the body. Researchers have now manipulated human stem cells so that they produce the types of brain cells that play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia, and autism.
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In this section

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  • Principal Investigator / Faculty (5)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (2)
  • Anderson Laboratory (1)
  • Center for Childhood Cancer Research (1)
  • Center for Computational and Genomic Medicine (1)
  • Department of Pathology and Laboratory Medicine (1)
  • Department of Pediatrics (1)
  • Division of Cancer Pathobiology (1)
  • Division of Endocrinology and Diabetes (1)
  • Human Pluripotent Stem Cell Core (1)
  • Institutional Review Board (1)
  • Jolley Laboratory (1)
  • Mir Laboratory (1)
  • Tasian Laboratory (1)
  • Thomas-Tikhonenko Laboratory (1)

In this section

Filter By

  • Principal Investigator / Faculty (5)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (2)
  • Anderson Laboratory (1)
  • Center for Childhood Cancer Research (1)
  • Center for Computational and Genomic Medicine (1)
  • Department of Pathology and Laboratory Medicine (1)
  • Department of Pediatrics (1)
  • Division of Cancer Pathobiology (1)
  • Division of Endocrinology and Diabetes (1)
  • Human Pluripotent Stem Cell Core (1)
  • Institutional Review Board (1)
  • Jolley Laboratory (1)
  • Mir Laboratory (1)
  • Tasian Laboratory (1)
  • Thomas-Tikhonenko Laboratory (1)
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