Related Topics | CHOP Research Institute
Request an Edit
Skip to main content

HOW CAN WE HELP YOU? Call 1-800-TRY-CHOP

Utility Nav

  • CHOP.EDU
  • Careers
  • Ways to Give
  • Healthcare Professionals
  • International
CHOP RI LogoChildren's Hospital of Philadelphia
Menu

Main navigation

  • Find People
  • Our Research
  • Clinical Trials
  • About
  • Innovation
  • Faculty & Staff Resources
  • Make a Gift
 

Results for Gene Editing

Share:
1 - 10 of 116

Lan Lin, PhD
Lan Lin

Dr. Lin studies RNA modifications (a.k.a "epitranscriptomics") in human diseases, including cancer. She develops and applies high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications, including A-to-I RNA editing and m6A RNA methylation.

E-mail:
linlan [at] chop.edu
Beverly L. Davidson, PhD
Photo of Beverly L. Davidson, PhD

Dr. Davidson works to understand the molecular basis of childhood onset neurodegenerative diseases and the development of gene and small molecule therapies for treatment. She also focuses on how noncoding RNAs participate in neural development and neurodegenerative disease processes, and how they can be harnessed for therapies.

E-mail:
davidsonbl [at] chop.edu
Deborah L. French, PhD
Deborah French

Dr. French came to CHOP in 2008 to establish the Human Pluripotent Stem Cell Core in the Center for Cellular and Molecular Therapeutics. She is an internationally recognized researcher involved in multi-investigator teams that utilize pluripotent stem cells for modeling human disease to study mechanism, development, and establish new therapeutic modalities.

E-mail:
frenchd [at] chop.edu
Christopher J. Cardinale, MD, PhD
Christopher J. Cardinale

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:
cardinalec [at] chop.edu
Evan Weber, PhD
Evan W. Weber

Dr. Weber is developing approaches to enhance CAR-T cell therapies for pediatric cancer by reprogramming T cells with improved durability and exhaustion resistance. His work will uncover molecular mechanisms that promote CAR-T cell exhaustion and identify new targets for therapeutic intervention.

E-mail:
weberew [at] chop.edu
Peter S. Choi, PhD
Peter S. Choi Headshot

Dr. Choi's research focuses on the role of RNA-binding proteins in the regulation of alternative splicing and how mutations in these factors contribute to cancer. He uses a combination of genetically-engineered models and high-throughput approaches to better understand how alternative splicing influences cellular function and to identify potential opportunities for therapeutic intervention.

E-mail:
choip [at] chop.edu
Amanda M. Ackermann, MD, PhD
Amanda M. Ackermann

Dr. Ackermann studies diabetes (types 1 and 2) and congenital hyperinsulinism using mouse models, cell lines, and primary human tissue. She aims to identify novel pathways regulating beta cell insulin secretion, leading to innovative therapeutic strategies for these disorders. Current studies include in vivo mouse physiology, ex vivo human islet physiology, CRISPR-Cas9 gene editing, epigenetic modification, and single-cell functional genomics.

E-mail:
ackermanna [at] chop.edu
Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
William H. Peranteau, MD
William H. Peranteau
Dr. Peranteau is an attending surgeon in the Division of Pediatric General, Thoracic and Fetal Surgery and an associate professor of Surgery at CHOP. His research interest is in fetal development as it relates to the potential understanding of and fetal intervention for congenital anomalies.
E-mail:
peranteauw [at] chop.edu

Science Stands Out in Our Most Engaging Cornerstone Stories of 2022

Published on
Dec 29, 2022
in Cornerstone Blog
Science Stands Out in Our Most Engaging Cornerstone Stories of 2022
These six Cornerstone stories garnered the most engagements from our CHOP Research Twitter, Facebook, and LinkedIn channels.
1 - 10 of 116

Pagination

  • Current page 1
  • Page 2
  • Page 3
  • Page 4
  • Page 5
  • Page 6
  • Page 7
  • Page 8
  • Page 9
  • Next page ››
  • Last page Last »
Back to previous page

In this section

Filter By

  • Principal Investigator / Faculty (9)
  • Research Administration (1)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (21)
  • Center for Injury Research and Prevention (19)
  • Center for Childhood Cancer Research (15)
  • Center for Autism Research (14)
  • PolicyLab (13)
  • Department of Pediatrics (11)
  • Center for Applied Genomics (9)
  • Center for Computational and Genomic Medicine (9)
  • Department of Pathology and Laboratory Medicine (9)
  • Division of Hematology (9)
  • Division of Oncology (9)
  • Clinical Futures (7)
  • Department of Biomedical and Health Informatics (7)
  • Division of Allergy and Immunology (7)
  • Department of Anesthesiology and Critical Care Medicine (5)
  • Division of Human Genetics (5)
  • Division of Infectious Diseases (5)
  • Division of Neurology (5)
  • Mitochondrial Medicine (5)
  • Office of Academic Training and Outreach Programs (5)
  • Roberts Individualized Medical Genetics Center (5)
  • Center for Mitochondrial and Epigenomic Medicine (4)
  • Division of Cancer Pathobiology (4)
  • Division of Pulmonary and Sleep Medicine (3)
  • PennCHOP Microbiome Program (3)
  • Cancer Immunotherapy (CAR-T) (2)
  • Center for Child Injury Prevention Studies (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Spatial and Functional Genomics (2)
  • Children’s Oncology Group (2)
  • CHOP Microbiome Center (2)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (2)
  • Division of Emergency Medicine (2)
  • Division of Endocrinology and Diabetes (2)
  • Division of Gastroenterology, Hepatology, and Nutrition (2)
  • Division of Neonatology (2)
  • Division of Nephrology (2)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (2)
  • Lifespan Brain Institute (2)
  • PEDSnet (2)
  • Thomas-Tikhonenko Laboratory (2)
  • Anderson Laboratory (1)
  • Blobel Laboratory (1)
  • Brain-Gene-Development Lab (1)
  • Camire Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Applied Genomics Laboratory (1)
  • Center for Human Phenomic Science (1)
  • Clinical In Vivo Gene Therapy (1)
  • Clinical Vector Core (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Radiology (1)
  • Department of Surgery (1)
  • Division of Adolescent Medicine (1)
  • Division of Cardiology (1)
  • Division of Neurosurgery (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Urology (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • George Laboratory (1)
  • Grant Laboratory (1)
  • Henrickson Laboratory (1)
  • Human Pluripotent Stem Cell Core (1)
  • Immune Dysregulation Program (1)
  • Institutional Review Board (1)
  • Jolley Laboratory (1)
  • Mir Laboratory (1)
  • Nissim Laboratory (1)
  • Office of Faculty Development (1)
  • Office of the Ruth M. Colket Chair Pediatric Nursing Science (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Vector Core (1)
  • Romberg Laboratory (1)
  • Samelson-Jones Laboratory (1)
  • Shalem Laboratory (1)
  • Stress Neurobiology Program (1)
  • Tasian Laboratory (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
  • Wells Laboratory (1)
  • Wyss/Campbell Center for Thoracic Insufficiency Syndrome (1)

In this section

Filter By

  • Principal Investigator / Faculty (9)
  • Research Administration (1)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (21)
  • Center for Injury Research and Prevention (19)
  • Center for Childhood Cancer Research (15)
  • Center for Autism Research (14)
  • PolicyLab (13)
  • Department of Pediatrics (11)
  • Center for Applied Genomics (9)
  • Center for Computational and Genomic Medicine (9)
  • Department of Pathology and Laboratory Medicine (9)
  • Division of Hematology (9)
  • Division of Oncology (9)
  • Clinical Futures (7)
  • Department of Biomedical and Health Informatics (7)
  • Division of Allergy and Immunology (7)
  • Department of Anesthesiology and Critical Care Medicine (5)
  • Division of Human Genetics (5)
  • Division of Infectious Diseases (5)
  • Division of Neurology (5)
  • Mitochondrial Medicine (5)
  • Office of Academic Training and Outreach Programs (5)
  • Roberts Individualized Medical Genetics Center (5)
  • Center for Mitochondrial and Epigenomic Medicine (4)
  • Division of Cancer Pathobiology (4)
  • Division of Pulmonary and Sleep Medicine (3)
  • PennCHOP Microbiome Program (3)
  • Cancer Immunotherapy (CAR-T) (2)
  • Center for Child Injury Prevention Studies (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Spatial and Functional Genomics (2)
  • Children’s Oncology Group (2)
  • CHOP Microbiome Center (2)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (2)
  • Division of Emergency Medicine (2)
  • Division of Endocrinology and Diabetes (2)
  • Division of Gastroenterology, Hepatology, and Nutrition (2)
  • Division of Neonatology (2)
  • Division of Nephrology (2)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (2)
  • Lifespan Brain Institute (2)
  • PEDSnet (2)
  • Thomas-Tikhonenko Laboratory (2)
  • Anderson Laboratory (1)
  • Blobel Laboratory (1)
  • Brain-Gene-Development Lab (1)
  • Camire Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Applied Genomics Laboratory (1)
  • Center for Human Phenomic Science (1)
  • Clinical In Vivo Gene Therapy (1)
  • Clinical Vector Core (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Radiology (1)
  • Department of Surgery (1)
  • Division of Adolescent Medicine (1)
  • Division of Cardiology (1)
  • Division of Neurosurgery (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Urology (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • George Laboratory (1)
  • Grant Laboratory (1)
  • Henrickson Laboratory (1)
  • Human Pluripotent Stem Cell Core (1)
  • Immune Dysregulation Program (1)
  • Institutional Review Board (1)
  • Jolley Laboratory (1)
  • Mir Laboratory (1)
  • Nissim Laboratory (1)
  • Office of Faculty Development (1)
  • Office of the Ruth M. Colket Chair Pediatric Nursing Science (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Vector Core (1)
  • Romberg Laboratory (1)
  • Samelson-Jones Laboratory (1)
  • Shalem Laboratory (1)
  • Stress Neurobiology Program (1)
  • Tasian Laboratory (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
  • Wells Laboratory (1)
  • Wyss/Campbell Center for Thoracic Insufficiency Syndrome (1)
CHOP Research Institute

3401 Civic Center Blvd.
Philadelphia, PA 19104

© 2023 Children's Hospital of Philadelphia. All Rights Reserved.

Privacy Policy | Terms of Use | HIPAA Notice of Privacy Practices | Ethics & Compliance

CHOP Directory

  • Main Hospital 1-800-879-2467
  • Foundation 267-426-6500
  • Research 215-590-3800
  • Referring Physicians 1-800-879-2467

Research Institute

  • About CHOP Research Institute
  • Our Research
  • Organizational Chart
  • News & Media
  • Events
  • Staff Resources

Find a...

  • Researcher
  • Clinical Trials
  • Research Labs
  • Core Facility
  • Academic Department

Our Organization

  • About CHOP
  • Giving
  • For Healthcare Professionals
  • Careers
  • International