Buckle your seatbelts because this has been a busy week for research news at Children's Hospital of Philadelphia. (It was also Teen Driver Safety Week, a topic we touched on with one of our blog posts earlier this week and in last week's In the News post.) Cancer research is hitting the accelerator with the release of the national Cancer
When something important is missing, we often search for a replacement. After many years of looking, a team of researchers at The Children’s Hospital of Philadelphia and the University of Missouri have found a way to substitute for a missing gene linked to a relentless childhood neurodegenerative disease.
The Vanderver Lab's translational research projects focus on characterizing the biological causes and clinical manifestations of leukodystrophies, a group of rare genetic disorders affecting the white matter of the brain. The lab's goal is to understand the molecular mechanisms of this disorder, identify new causative genes, improve the efficacy of novel diagnostic tools, refine and standardize clinical care guidelines, and accelerate the development of disease-specific clinical trials.