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Results for Diabetes

1 - 10 of 224

Sara E. Pinney, MD, MS
Sara E. Pinney

Dr. Pinney investigates the molecular mechanisms that link an adverse intrauterine milieu to the development of diabetes and obesity later in life. Specifically, she is researching how intrauterine growth restriction, gestational diabetes and in utero exposure to environmental toxicants contribute to the development of diabetes and obesity in offspring.

E-mail:
pinneys [at] chop.edu
Steven M. Willi, MD
Steven M. Willi, MD

Dr. Willi's research focuses on therapeutics for type 1 and type 2 diabetes and he has performed a number of physiologic studies in the etiology and characterization of diabetes in children. His current studies include trials on the delay of progression of type 1 diabetes and a multicenter trial to examine the optimal therapeutics for type 2 diabetes in children.

E-mail:
willi [at] chop.edu
Diva D. De León-Crutchlow, MD, MSCE
Diva D. De León-Crutchlow

Dr. De Leon-Crutchlow’s translational research program focuses on examining the pathophysiology of disorders of insulin regulation, identifying novel therapeutic targets, and developing new therapies for these conditions. The program approach includes patient-oriented research and bench research employing mouse models and primary islet cultures.

E-mail:
deleon [at] chop.edu
Amanda M. Ackermann, MD, PhD
Amanda M. Ackermann

Dr. Ackermann studies diabetes (types 1 and 2) and congenital hyperinsulinism using mouse models, cell lines, and primary human tissue. She aims to identify novel pathways regulating beta cell insulin secretion, leading to innovative therapeutic strategies for these disorders. Current studies include in vivo mouse physiology, ex vivo human islet physiology, CRISPR-Cas9 gene editing, epigenetic modification, and single-cell functional genomics.

E-mail:
ackermanna [at] chop.edu
David R. Weber, MD, MSCE
David R. Weber

Dr. Weber is a clinical researcher focused on improving bone health in children. He is currently focused on investigating the effects of effects of type 1 diabetes and Duchenne muscular dystrophy on the skeleton. 

E-mail:
weberd [at] chop.edu
Struan F.A. Grant, PhD
Photo of Struan F.A. Grant

Dr. Grant uses high-throughput genotyping and sequencing technologies, combined with statistical and bioinformatic approaches, to unravel genomic puzzles related to multiple common complex traits.

E-mail:
grants [at] chop.edu
Lorraine L. Katz, MD
Lorraine L. Katz

Dr. Katz’s investigates the sequelae of obesity and type 2 diabetes mellitus in youth. Her research involves the intersection of sleep, obesity, and glucose intolerance and prevention of cardiovascular risk. Her studies have led to the evaluation of quantitative tools important for assessment of metabolic risk in youth.

E-mail:
katzl [at] chop.edu
Michael Silverman, MD, PhD
Michael Silverman

Dr. Silverman studies the fundamental aspects of early-life commensal microbes that influence immune system development and function. He discovered that the MHC-II E molecule prevents type 1 diabetes by shaping the intestinal microbiota early in life.

E-mail:
silvermam1 [at] chop.edu
Rebecca A. Simmons, MD
Rebecca A. Simmons

The principal goal of Dr. Simmons' research program is to elucidate the underlying molecular mechanisms that link an aberrant intrauterine milieu to the later development of diseases in adulthood. She has made many seminal contributions to the understanding of the role that epigenetic modifications play in developmental programming of obesity and type 2 diabetes.

E-mail:
simmonsr [at] chop.edu
Jacquelyn Anne Hatch-Stein, MD
Jacquelyn Anne Hatch-Stein

Dr. Hatch-Stein's research interests include diabetes, thyroid disorders, and disorders of growth and puberty. Recent clinical research projects include "Bone Health and Cardiovascular Risk in Turner Syndrome" and "Patterns of Height Velocity in Down Syndrome."

E-mail:
hatchsteinj [at] chop.edu
1 - 10 of 224

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In this section

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  • Principal Investigator / Faculty (36)
  • Researcher / Lab Personnel (2)
  • Nurse Researcher (1)
  • Research Administration (1)

Organizations

  • Division of Endocrinology and Diabetes (41)
  • Center for Applied Genomics (19)
  • Department of Pediatrics (17)
  • PolicyLab (12)
  • Center for Injury Research and Prevention (8)
  • Center for Pediatric Clinical Effectiveness (8)
  • Center for Autism Research (7)
  • Department of Biomedical and Health Informatics (7)
  • Division of Human Genetics (7)
  • Division of Neonatology (7)
  • Center for Childhood Cancer Research (6)
  • Center for Mitochondrial and Epigenomic Medicine (6)
  • Division of Gastroenterology, Hepatology, and Nutrition (6)
  • Division of Oncology (6)
  • Division of Pulmonary and Sleep Medicine (6)
  • PennCHOP Microbiome Program (6)
  • Spatial and Functional Genomics Collaborative (6)
  • Congenital Hyperinsulinism Research Laboratory (5)
  • Division of Allergy and Immunology (5)
  • Comprehensive Bone Marrow Failure Center (4)
  • Cystic Fibrosis-Related Diabetes Research Program (4)
  • Department of Child and Adolescent Psychiatry (4)
  • Division of Adolescent Medicine (4)
  • Division of Infectious Diseases (4)
  • Division of Nephrology (4)
  • Division of Orthopaedic Surgery (4)
  • Center for Data-Driven Discovery in Biomedicine (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Division of Cardiology (3)
  • Division of Hematology (3)
  • Division of Urology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • mHealth Research Affinity Group (3)
  • Mitochondrial Medicine (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Advancement of Hyperinsulinism Care and Research (2)
  • Center for Human Phenomic Science (2)
  • Chronic Kidney Disease in Children Study (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Division of Neurology (2)
  • Division of Neurosurgery (2)
  • Division of Rheumatology (2)
  • Grant Laboratory (2)
  • Inflammatory Bowel Disease Center (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Romberg Laboratory (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Wells Laboratory (2)
  • Blobel Laboratory (1)
  • Brodeur Laboratory (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Applied Genomics Laboratory (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Violence Prevention (1)
  • CHOP Microbiome Center (1)
  • Chou Laboratory (1)
  • DBHi Bioinformatics (1)
  • De León-Crutchlow Laboratory (1)
  • Department of Surgery (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Emergency Medicine (1)
  • eMERGE (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Intellectual and Developmental Disabilities Research Center (1)
  • John Laboratory (1)
  • Lifespan Brain Institute (1)
  • Metabolomic Core (1)
  • Office of Academic Training and Outreach Programs (1)
  • Oliver Laboratory (1)
  • Pediatric Center of Excellence in Nephrology (1)
  • Pediatric Research Consortium (1)
  • PEDSnet (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Creative Services (1)
  • Silverman Laboratory (1)
  • Sleep Center (1)
  • Stress Neurobiology Program (1)
  • The Resuscitation Science Center (1)
  • Vaccine and Treatment Evaluation Unit (1)
  • Wyss/Campbell Center for Thoracic Insufficiency Syndrome (1)

In this section

Filter By

  • Principal Investigator / Faculty (36)
  • Researcher / Lab Personnel (2)
  • Nurse Researcher (1)
  • Research Administration (1)

Organizations

  • Division of Endocrinology and Diabetes (41)
  • Center for Applied Genomics (19)
  • Department of Pediatrics (17)
  • PolicyLab (12)
  • Center for Injury Research and Prevention (8)
  • Center for Pediatric Clinical Effectiveness (8)
  • Center for Autism Research (7)
  • Department of Biomedical and Health Informatics (7)
  • Division of Human Genetics (7)
  • Division of Neonatology (7)
  • Center for Childhood Cancer Research (6)
  • Center for Mitochondrial and Epigenomic Medicine (6)
  • Division of Gastroenterology, Hepatology, and Nutrition (6)
  • Division of Oncology (6)
  • Division of Pulmonary and Sleep Medicine (6)
  • PennCHOP Microbiome Program (6)
  • Spatial and Functional Genomics Collaborative (6)
  • Congenital Hyperinsulinism Research Laboratory (5)
  • Division of Allergy and Immunology (5)
  • Comprehensive Bone Marrow Failure Center (4)
  • Cystic Fibrosis-Related Diabetes Research Program (4)
  • Department of Child and Adolescent Psychiatry (4)
  • Division of Adolescent Medicine (4)
  • Division of Infectious Diseases (4)
  • Division of Nephrology (4)
  • Division of Orthopaedic Surgery (4)
  • Center for Data-Driven Discovery in Biomedicine (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Division of Cardiology (3)
  • Division of Hematology (3)
  • Division of Urology (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • mHealth Research Affinity Group (3)
  • Mitochondrial Medicine (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Advancement of Hyperinsulinism Care and Research (2)
  • Center for Human Phenomic Science (2)
  • Chronic Kidney Disease in Children Study (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Division of Neurology (2)
  • Division of Neurosurgery (2)
  • Division of Rheumatology (2)
  • Grant Laboratory (2)
  • Inflammatory Bowel Disease Center (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Romberg Laboratory (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Wells Laboratory (2)
  • Blobel Laboratory (1)
  • Brodeur Laboratory (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Applied Genomics Laboratory (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Violence Prevention (1)
  • CHOP Microbiome Center (1)
  • Chou Laboratory (1)
  • DBHi Bioinformatics (1)
  • De León-Crutchlow Laboratory (1)
  • Department of Surgery (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Emergency Medicine (1)
  • eMERGE (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Intellectual and Developmental Disabilities Research Center (1)
  • John Laboratory (1)
  • Lifespan Brain Institute (1)
  • Metabolomic Core (1)
  • Office of Academic Training and Outreach Programs (1)
  • Oliver Laboratory (1)
  • Pediatric Center of Excellence in Nephrology (1)
  • Pediatric Research Consortium (1)
  • PEDSnet (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Creative Services (1)
  • Silverman Laboratory (1)
  • Sleep Center (1)
  • Stress Neurobiology Program (1)
  • The Resuscitation Science Center (1)
  • Vaccine and Treatment Evaluation Unit (1)
  • Wyss/Campbell Center for Thoracic Insufficiency Syndrome (1)
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