Results for DNA Replication

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Wei Tong, PhD
Wei Tong

Dr. Tong investigates cytokine receptor signaling in normal and neoplastic hematopoietic development. She uses integrated approaches encompassing biochemistry, molecular biology, mouse models, and primary human samples to understand signaling events emanating from cytokine receptors that regulate the development of hematopoietic stem/progenitor cells.

E-mail:
tongw [at] chop.edu
Matthew D. Weitzman, PhD
Matthew D. Weitzman Headshot

Dr. Weitzman's research program aims to understand host responses to virus infection, and the cellular environment encountered and manipulated by viruses. He studies multiple viruses in an integrated experimental approach that combines biochemistry, molecular biology, genetics, and cell biology.

E-mail:
weitzmanm [at] chop.edu
Narasaiah Kovuru, PhD
Narasaiah Kovuru

Narasaiah Kovuru’s research focuses on understanding the origins of hematopoietic failure/bone marrow failure in Fanconi Anemia working with the murine model.

E-mail:
kovurun [at] chop.edu

What Viruses Can Tell Us About RNA Processing: Q&A with the Weitzman Lab

Published on
Jul 14, 2022
in Cornerstone Blog
Recent research from the Weitzman Lab sheds light on how a virus manipulates and takes control of RNA processing pathways.
Weitzman Lab scientists share their discoveries about how viruses can manipulate RNA processing.

Where Discovery Leads: Building on Nature's Delivery System to Advance Gene Therapy

Published on
Nov 5, 2021
in Cornerstone Blog
Raymond G. Perelman Center for Cellular and Molecular Therapeutics
The Clinical Vector Core, an award-winning, state-of-the-art, multi-product GMP manufacturing facility, supports the growing field of gene therapy.

Looking Ahead to a Vaccine for the Coronavirus: Q&A With Paul Offit, MD

Published on
Dec 21, 2020
in Cornerstone Blog
Looking Ahead to a Vaccine for the Coronavirus: Q&A With Paul Offit, MD
Paul Offit, MD, director of the Vaccine Education Center, and a world-renowned vaccine expert, discusses the pending genetic vaccines for COVID-19.

CHOP Physician-Scientist in Search of Cure for Fanconi Anemia

Published on
Oct 15, 2020
in Cornerstone Blog
CHOP Physician-Scientist in Search of Cure for Fanconi Anemia
Peter Kurre, MD, seeks to determine to what extent defects in fetal blood forming cells accelerate the loss of bone marrow function in young patients.

In the News: Newly Linked Epilepsy Genes, Pediatric Safety Research, Teen Intern Recruits for Research, CHOP Visits UAE, Trends in Opioid Prescription

Published on
Feb 8, 2019
in Cornerstone Blog
CHOP Research In the News
In this week’s recap, collaboration at the local and international levels takes center stage.

Targeting Abnormal Signals Suggests Novel Method to Treat a Rare Childhood Blood Disease

Published on
Oct 9, 2018
in Press Releases
In Animal Study, CHOP Hematologist Restores Blood Cell Function in Fanconi Anemia

Snapshot Science: What Are Transcription Errors' Role in Aging and Disease?

Published on
Oct 3, 2017
in Cornerstone Blog
Transcription errors
The human genome provides a precise, biological blueprint of life. To implement this blueprint correctly, the genome must be read with great precision, but it's impossible for this process to be completely error-free. Mistakes during transcription - random errors in how DNA sequences are copied for a gene to be expressed - can happen any time in any number of ways.
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