Dr. Jolley's research lab is focused on visualizing and quantifying congenitally abnormal heart structures using 3D imaging with the driving goal of informing surgical and interventional planning in children and adults with congenital heart disease.
Dr. Rossano's extensive research experience primarily involves the epidemiology and outcomes of cardiovascular disease in children, and multi-institutional collaborative observational and interventional studies. His particular research interests include evaluating the treatment and outcomes of pediatric cardiomyopathy, heart failure, and transplantation.
Dr. O'Byrne is a pediatric cardiologist with research interests in cardiac disease outcomes, perioperative outcomes, and children with pulmonary hypertension. He combines the use of large observational datasets to study outcomes, practice variation, cost, and the determinants of health-related quality of life in this population.
Dr. Glatz is a pediatric interventional cardiologist conducting rigorously designed clinical research. He has formal Masters-level training in study design, epidemiology, and biostatistics. Dr. Glatz has an extensive record of research productivity, including multiple collaborative projects, focused on outcomes research in the content area of pediatric cardiology.
Dr. Goldberg's research focuses on children with single ventricle congenital heart disease. Much of his work centers on the consequences of the abnormal single ventricle physiology and the impact on other organ systems throughout the body. He is also interested in medical interventions designed to improve the efficiency of the post-Fontan circulation by lowering pulmonary vascular resistance.
Dr. Goldmuntz's research focuses on the genetic basis and modifiers of congenital heart disease, cardiomyopathy, and heart failure. Her goal is to identify genetic alterations conferring a risk for congenital heart disease and to correlate these findings with clinical outcomes. To this end, she is also performing clinical translational studies.
Dr. Kurth is a physician-scientist-leader in pediatric anesthesiology, quality and safety, and pediatric healthcare. He has experience conducting basic, clinical, and translational research studies as well as quality improvement projects to investigate clinical problems and develop technologies to understand the problem and devise therapies to prevent or treat it.
Dr. Stallings is working on intervention trials involving three chronic diseases with nutrition-related abnormalities resulting in meaningful adverse outcomes: cystic fibrosis (new drugs), sickle cell disease (vitamin A) and chronic pancreatitis (enzyme replacement drug).
Dr. Krantz's lab identifies and characterizes the molecular etiology of syndromic and non-syndromic developmental disorders. He has identified genes for several genetic conditions (Cornelia de Lange Syndrome, CHOPS syndrome, Alagille syndrome, hearing loss) implicating critical molecular pathways in human disorders for the first time. He has been at the forefront of studying the integration of genomics into clinical settings.
As director of the Center for Clinical Pharmacology, Dr. Zuppa has a dynamic research program that focuses on using clinical pharmacological modeling and simulation strategies to study the impact of critical illness on drug disposition in children.