Dr. Flake is a general pediatric surgeon with a clinical and research focus on prenatal treatment ranging from the fetal surgical repair of anatomic anomalies to prenatal stem cell and gene therapy. He has extensive experience in developing rodent, canine, and sheep models for in utero transplantation and for investigating fetal surgery for anatomic malformations.
The founder and director of CHOP's Center for Fetal Diagnosis and Treatment, Dr. Adzick is an innovator in the field of fetal medicine, pursuing groundbreaking prenatal treatment for debilitating birth defects. He led the NIH-funded "Management of Myelomeningocele Study" (MOMS) at CHOP, a breakthrough research program that showed fetal surgery for spina bifida results in significantly improved outcomes.
Dr. Krantz's lab identifies and characterizes the molecular etiology of syndromic and non-syndromic developmental disorders. He has identified genes for several genetic conditions (Cornelia de Lange Syndrome, CHOPS syndrome, Alagille syndrome, hearing loss) implicating critical molecular pathways in human disorders for the first time. He has been at the forefront of studying the integration of genomics into clinical settings.
Ear infections, e-cigarettes, and exciting collaborations, oh my! In this week's research news roundup, we followed the trails of our clinicians and investigators as they used expertise and evidence to weigh in on mainstream health issues. From how to design safer seats and belts in cars, to why e-cigarette sales should follow strict regulations, to discussions on the implications of
This week we're all about getting smart in our highlights of research news from The Children's Hospital of Philadelphia. Getting smart in the approach to tackling childhood cancer means identifying strategies that will make a decade's progress in half the time - which is exactly the focus of the national Cancer Moonshot.