Dr. Sullivan's research focuses on new and rare immunodeficiencies. She has a long-standing interest in one of the most common of the primary immunodeficiencies – chromosome 22q11.2 deletion syndrome. She also investigates common variable immunodeficiency, as well as the genetics and epigenetics of systemic lupus erythematosus.
Dr. Douglas has extensive laboratory experience investigating the cellular immunology of HIV/AIDS, primary immune deficiency diseases, and cellular immunopathologies. In addition, he has had significant involvement in studies related to immunological interactions.
In times of uncertainty, a dose of positive news reminds us that making progress through difficult situations is possible - our Children's Hospital of Philadelphia research community does it every day! Whether it's researchers who push the barriers of current autism diagnoses, an 8-year-old survivor who fought off a shrewd cancer, or physicians who act as policy watchdogs to protect
We've had a flurry of activity this week at Children's Hospital of Philadelphia Research Institute, including our first snowstorm of the year. In between shoveling, we took a few minutes to dig into the latest research news.
Finding out Cornelia de Lange Syndrome (CdLS) causes could be extremely important to understanding human development at all levels, which is why Ian Krantz, MD, medical director of the Center for Cornelia de Lange Syndrome and Related Diagnosis at CHOP, and his colleagues have dedicated the past two decades to research that is piecing together the basic biology of CdLS.
The Inflammation and Immunity Lab has a broad interest in immune dysfunction. This can underlie susceptibility to infections and autoimmunity and inflammation. The investigators in the lab use cutting-edge approaches to investigate cause in individual patients and to look at population-wide causes of disease.