Results for Clinical Research

Dr. Aplenc investigates ways to improve the outcomes of children with cancer, particularly acute myeloid leukemia, with clinical epidemiology studies and translational research.

Dr. Laskin's research focuses on the conduct of clinical investigations and translational studies designed to target mechanisms to prevent, treat, or slow the progression of chronic kidney disease in immunosuppressed patients, including children receiving a bone marrow or kidney transplant.

Dr. Chang is a clinical investigator focusing on cardiovascular assessment and outcomes of pediatric-onset systemic lupus erythematosus (pSLE). Her research assesses the utility of various screening modalities, including echocardiography, ambulatory blood pressure monitoring, and tonometry, for the early detection of cardiovascular disease. Her research goals are to develop screening protocols and targeted interventions to prevent pSLE-related cardiovascular morbidity and mortality.

Whitney Guthrie, PhD, is a clinical psychologist and scientist at the Center for Autism Research. Dr. Guthrie’s research focuses on the early developmental trajectories that characterize autism spectrum disorder with the ultimate goal of improving early detection and intervention.

Dr. Weber is a clinical researcher focused on improving bone health in children. He is currently focused on investigating the effects of effects of type 1 diabetes and Duchenne muscular dystrophy on the skeleton. 

Dr. Silber is the director of the Center for Outcomes Research at CHOP, and is an internationally known authority on outcomes measurement and severity adjustment for both adult and pediatric applications.

Dr. Leff's background is in child clinical psychology, and he has broad training and expertise in intervention research, mixed methods, and in leading a range of federally funded research initiatives. His research goal is to use community-based participatory research (CBPR) to develop and validate school-based aggression and bullying intervention programs and assessment tools for urban minority youth.

Dr. Jill Savla is an attending cardiologist at Children's Hospital of Philadelphia. Her research interests include congenital heart disease, early life risk factors for congenital heart surgery, maternal-fetal environment, outcomes research, and clinical epidemiology.

Dr. Hatch-Stein's research interests include diabetes, thyroid disorders, and disorders of growth and puberty. Recent clinical research projects include "Bone Health and Cardiovascular Risk in Turner Syndrome" and "Patterns of Height Velocity in Down Syndrome."

Dr. Zee's statistical methods research includes topics in survival analysis, measurement error, observational data methods, and machine learning. Her clinical research is focused on kidney disease, specifically in clinical and pathology markers of glomerular and chronic kidney disease progression.