Dr. Zorc's work focuses on the intersection of interventional clinical research, quality improvement (QI), and clinical informatics. He has formal certification in epidemiology, QI methodology, and clinical informatics, and has participated in multi-center research networks, guideline and improvement collaboratives, and electronic health record development locally and nationally.
Dr. Adamson serves as chair of the international consortium Children's Oncology Group and on the National Cancer Advisory Board. In addition to his national and international leadership roles in pediatric oncology, Dr. Adamson maintains a dynamic research program on pediatric clinical-translational drug development, with a strong focus on childhood cancer drug development.
The research interests of Dr. Downes focus on antimicrobial clinical pharmacology and pharmacoepidemiology in children with a goal to identify novel approaches to optimize efficacy, minimize toxicity, and limit antimicrobial resistance from antibiotics.
Dr. Osterhoudt is an attending physician in the Division of Emergency Medicine and the medical director of the Poison Control Center at Children's Hospital of Philadelphia. His interests include the clinical epidemiology and risk assessment of pediatric poisoning exposures, and infantile methemoglobinemia.
As director of the Center for Clinical Pharmacology, Dr. Zuppa has a dynamic research program that focuses on using clinical pharmacological modeling and simulation strategies to study the impact of critical illness on drug disposition in children.
Dr. Levine has an active laboratory research program that complements and extends his clinical studies. He has identified the molecular basis of several inherited disorders of mineral metabolism. His research interests extend to the molecular basis for embryological development of the parathyroid glands.
Dr. Zaoutis is a pediatrician trained in infectious disease and epidemiology with a robust research program focused on the epidemiology, prevention, and treatment of healthcare acquired infections; antimicrobial resistance; and antimicrobial use.
Dr. Chang is a clinical investigator focusing on cardiovascular assessment and outcomes of pediatric-onset systemic lupus erythematosus (pSLE). Her research assesses the utility of various screening modalities, including echocardiography, ambulatory blood pressure monitoring, and tonometry, for the early detection of cardiovascular disease. Her research goals are to develop screening protocols and targeted interventions to prevent pSLE-related cardiovascular morbidity and mortality.
Dr. Mostoufi-Moab's clinical and research program is focused on endocrine late effects after childhood cancer therapy. She has unique dual training in pediatric endocrinology and oncology with a master's degree in clinical epidemiology. The goal of her research program is to pursue a mechanistic understanding of metabolic and endocrine disorders that occur due to cancer therapy.