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Results for Cellular Metabolism

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Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
Daniel P. Kelly, MD
Daniel P. Kelly

Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.

E-mail:
dankelly [at] pennmedicine.upenn.edu
Fanxin Long, PhD
Fanxin Long

Bone disorders exact a considerable toll on human health in both children and adults. Dr. Long seeks to understand the fundamental mechanisms underlying both normal skeletal development and the pathophysiology of bone diseases. His current research includes studies of skeletal stem cells and progenitors, metabolic regulation of bone cells, and the integration of bone and whole-body metabolism.

E-mail:
longf1 [at] chop.edu
Akiva S. Cohen, PhD
Akiva S. Cohen

Dr. Cohen's laboratory focuses on how traumatic brain injury alters hippocampal and cortical circuitry, thereby causing cognitive impairment.

E-mail:
cohena [at] chop.edu
Liming Pei, PhD
Liming Pei

Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.

E-mail:
peil [at] chop.edu
Paula M. Oliver, PhD
Paula M. Oliver

Dr. Oliver investigates the mechanisms governing T cell activation and protective immunity. Her goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

E-mail:
oliverp1 [at] chop.edu
Lan Lin, PhD
Lan Lin

Dr. Lin studies RNA modifications (a.k.a "epitranscriptomics") in human diseases, including cancer. She develops and applies high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications, including A-to-I RNA editing and m6A RNA methylation.

E-mail:
linlan [at] chop.edu

CHOP Research Paved Way for First FDA-approved Treatment for Friedreich’s Ataxia

Published on
May 19, 2023
in Cornerstone Blog
CHOP Research Paved Way for First Approved Drug for FA
CHOP research paved the way for the first treatment for Friedreich’s ataxia (FA), an inherited neurodegenerative disease.

ASCGT 26th Annual Meeting Well-Attended by CHOP Scientists

Published on
May 18, 2023
in Cornerstone Blog
ASCGT 26th Annual Meeting Well-Attended by CHOP Scientists
Scientists from Children’s Hospital of Philadelphia attend the American Society of Cell & Gene Therapy Annual Meeting to share their expertise through posters, panel discussions, and workshops.

Tableside Chat About Mitochondria Leads to Gates Foundation Grant for COVID-19 Research

Published on
Mar 2, 2023
in Cornerstone Blog
Tableside Chat Leads to Gates Foundation Grant for CHOP
With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.
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In this section

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  • Song Laboratory (1)
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In this section

Filter By

  • Principal Investigator / Faculty (7)

Organizations

  • Center for Mitochondrial and Epigenomic Medicine (10)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (7)
  • Mitochondrial Medicine (6)
  • Department of Pathology and Laboratory Medicine (5)
  • Division of Endocrinology and Diabetes (5)
  • Division of Neurology (5)
  • Center for Childhood Cancer Research (4)
  • Center for Applied Genomics (3)
  • PolicyLab (3)
  • Center for Computational and Genomic Medicine (2)
  • Center for Injury Research and Prevention (2)
  • Center for Spatial and Functional Genomics (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Department of Pediatrics (2)
  • Division of Oncology (2)
  • Friedreich’s Ataxia Center of Excellence (2)
  • Wallace Laboratory (2)
  • Bailis Laboratory (1)
  • Center for Autism Research (1)
  • Clinical Futures (1)
  • Davidson Laboratory (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Surgery (1)
  • Division of Allergy and Immunology (1)
  • Division of Cardiology (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Human Genetics (1)
  • Division of Infectious Diseases (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Protective Immunity (1)
  • Division of Rheumatology (1)
  • Lin Laboratory (1)
  • Lynch Laboratory (1)
  • Ma Laboratory for Immune Engineering (1)
  • Nissim Laboratory (1)
  • Office of Academic Training and Outreach Programs (1)
  • Song Laboratory (1)
  • Wyss/Campbell Center for Thoracic Insufficiency Syndrome (1)
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