Dr. Rossano's extensive research experience primarily involves the epidemiology and outcomes of cardiovascular disease in children, and multi-institutional collaborative observational and interventional studies. His particular research interests include evaluating the treatment and outcomes of pediatric cardiomyopathy, heart failure, and transplantation.
Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.
Dr. Ortiz-Gonzalez is a physician-scientist specializing in pediatric neurogenetics. Her clinical work focuses on finding a unifying genetic diagnosis for children with rare neurodevelopmental disorders. Her research is informed by her patients and focuses on understanding how genetic changes, in particular those affecting mitochondrial function, cause disease so we can develop better treatments for these children in the future.
Dr. Goldmuntz's research focuses on the genetic basis and modifiers of congenital heart disease, cardiomyopathy, and heart failure. Her goal is to identify genetic alterations conferring a risk for congenital heart disease and to correlate these findings with clinical outcomes. To this end, she is also performing clinical translational studies.
Dr. Ahrens-Nicklas works to understand why patients with inherited biochemical disorders often suffer severe, untreatable neurologic and cardiac symptoms. She strives to elucidate the link between biochemistry and network excitability, in order to drive new approaches to therapy.