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Results for CTL019

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Stephan A. Grupp, MD, PhD
Stephan A. Grupp

Dr. Grupp develops and conducts preclinical testing of engineered cell therapies and signal transduction inhibitors in leukemia, in pediatric immunotherapy trials, and in the manufacture and use of cellular therapeutics in preclinical, good manufacturing practices, and clinical trial settings. Dr. Grupp leads most CTL019 (CD19 CAR) clinical trials, and his colleagues are the global leaders in highly active CAR T cell therapy.

E-mail:
grupp [at] chop.edu

CHOP Cell and Gene Therapy Experts Elected to National Academy of Medicine

Published on
Oct 21, 2019
in Cornerstone Blog
Stephen A. Grupp and Beverly Davidson
Join us in congratulating cell and gene therapy experts Beverly Davidson, PhD, and Stephan Grupp, MD, PhD, newly elected to the National Academy of Medicine.

In the News: Gene Therapy EU Approval, Long-Term CAR T-cell Effectiveness, 10 Years of CAR, AHA Conference, CAR T-cell Resistance

Published on
Dec 14, 2018
in Cornerstone Blog
CHOP Research In the News
In this week’s research roundup: personalized gene therapies reach key milestones and scientists probe CAR T-cell resistance.

European Commission Approves Innovative CAR T-cell Therapy Pioneered at Children’s Hospital of Philadelphia

Published on
Aug 24, 2018
in Press Releases
CHOP Greets Approval as a Landmark Medical Advance for Young Cancer Patients in Europe

CSO Perspectives: A Moment to Remember: First-of-its-Kind Cancer Treatment Approved by FDA

Published on
Aug 31, 2017
in Cornerstone Blog
Bryan A. Wolf
It was a pivotal moment that has turned into a new era for cancer immunotherapy. On April 17, 2012, Children's Hospital of Philadelphia researchers for the first time treated a pediatric patient with a cellular therapy that used her own reprogrammed immune cells, called T cells, to attack her aggressive form of blood cancer.

FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University of Pennsylvania and Children’s Hospital of Philadelphia

Published on
Aug 29, 2017
in Press Releases
Pioneering CAR T-cell Studies Led to First-ever Cancer Cell and Gene Therapy Approval

Psychology in Media Award, Targeted Cancer Drugs, Dermatology App, CHOP ROP Model, Beckwith-Wiedemann Conference

Published on
Jul 28, 2017
in Cornerstone Blog
CHOP Research In the News
From cancer drugs designed to match a child's specific molecular abnormality, to a phone app that can offer a dermatologic diagnosis quicker than an office visit, the future of children's healthcare is unfolding right before our eyes at the Children's Hospital of Philadelphia Research Institute.

In the News: CTL019 Wins FDA Panel Support, Driving with ADHD, High School Football, New Genetic Syndrome, Teen Bone Growth, Missed Nursing Care

Published on
Jul 13, 2017
in Cornerstone Blog
CHOP Research In the News
CAR T-cell therapy tops this week's research roundup, with news about the experimental immunotherapy designed to re-engineer a patient's cells to fight cancer making late-breaking and captivating headlines across the nation.

In the News: Sports Medicine Research Award, Concussion Research Collaboration, Stephan Grupp, PAS Meeting, Type 1.5 Diabetes

Published on
May 19, 2017
in Cornerstone Blog
CHOP Research In the News
Our latest research news roundup carries a hint of summer and exciting new beginnings: As more than 70 Children's Hospital of Philadelphia experts traveled to sunny California for the annual Pediatric Academic Societies (PAS) Meeting, back at home, sports medicine research ramped up with new investigations into how we can protect kid's health on (and off) the field.

In the News: Breastfeeding Practices, Cardiac Life Support, Vaccination Schedules, Face Recognition Diagnosis, American Academy Election, AAPOS Award

Published on
Apr 21, 2017
in Cornerstone Blog
CHOP Research In the News
A simple question raised by a concerned parent can often kick-start lines of research at Children's Hospital of Philadelphia. This week in the news, those sorts of everyday queries - whether they're about how to breastfeed, why parents should follow a vaccine schedule, or how mechanical circulatory support devices work - led to exciting headline-making stories.
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In this section

Filter By

  • Principal Investigator / Faculty (1)

Organizations

  • Center for Childhood Cancer Research (6)
  • Division of Oncology (5)
  • Cancer Immunotherapy (CAR-T) (4)
  • Center for Injury Research and Prevention (3)
  • Children’s Oncology Group (2)
  • PolicyLab (2)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (2)
  • Center for Autism Research (1)
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  • Clinical In Vivo Gene Therapy (1)
  • Department of Anesthesiology and Critical Care Medicine (1)
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  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
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