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Results for CD19 CAR

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Stephan A. Grupp, MD, PhD
Stephan A. Grupp

Dr. Grupp develops and conducts preclinical testing of engineered cell therapies and signal transduction inhibitors in leukemia, in pediatric immunotherapy trials, and in the manufacture and use of cellular therapeutics in preclinical, good manufacturing practices, and clinical trial settings. Dr. Grupp leads most CTL019 (CD19 CAR) clinical trials, and his colleagues are the global leaders in highly active CAR T cell therapy.

E-mail:
grupp [at] chop.edu
Jessica B. Foster, MD
Jessica B. Foster

Dr. Foster’s current research focuses on immunotherapy for pediatric solid and brain tumors. Specifically she is investigating chimeric antigen receptor (CAR) T cell therapy for neuroblastoma, high-grade gliomas, medulloblastomas, diffuse intrinsic pontine gliomas, and other brain tumors. The goals of her research are to develop pre-clinical CAR T cells for translation into clinical trials to help these devastating tumors.

E-mail:
fosterjb [at] chop.edu

In The News: MIS-C, Antibody Treatment for Eosinophilic Esophagitis, ASH 2022

Published on
Jan 6, 2023
in Cornerstone Blog
Our Scientists’ Research Highlighted In the News
See highlights of work by Children’s Hospital of Philadelphia researchers that is leading to novel findings.

Science Stands Out in Our Most Engaging Cornerstone Stories of 2022

Published on
Dec 29, 2022
in Cornerstone Blog
Science Stands Out in Our Most Engaging Cornerstone Stories of 2022
These six Cornerstone stories garnered the most engagements from our CHOP Research Twitter, Facebook, and LinkedIn channels.

Where Discovery Leads: Taking CAR T-Cell Therapy to Solid Tumors and Beyond

Published on
Sep 19, 2022
in Cornerstone Blog
Where Discovery Leads: CAR T-Cell Therapy Research
CHOP physician-scientists discuss their CAR T-cell therapy research for childhood cancers in Where Discovery Leads.

CHOP Researchers Elucidate Mechanism Behind Immunotherapy Resistance in B-ALL

Published on
Jan 24, 2022
in Cornerstone Blog
Researchers Find Mechanism of Treatment Resistance in B-ALL
Researchers identified aberrant splicing as a culprit behind treatment resistance in B-ALL.

In The News: ADHD, Humanized CAR T-Cell, Obesity, Malaria, Fetal Surgery

Published on
Jul 9, 2021
in Cornerstone Blog
In the News
This week’s news roundup features new findings in youth suicide risk, CAR T-cell therapy, obesity rates during the pandemic, and more.

Borrowing a Weapon From Leukemia’s Arsenal to Develop New Immunotherapy Approaches

Published on
Jan 30, 2019
in Cornerstone Blog
Andrei Thomas-Tikhonenko
Basic and bioinformatics scientists at CHOP and Penn are working hard to unravel how leukemia cells resist CAR T-cell therapy.

In the News: Gene Therapy EU Approval, Long-Term CAR T-cell Effectiveness, 10 Years of CAR, AHA Conference, CAR T-cell Resistance

Published on
Dec 14, 2018
in Cornerstone Blog
CHOP Research In the News
In this week’s research roundup: personalized gene therapies reach key milestones and scientists probe CAR T-cell resistance.

Data Release to Enable Smarter Trials for Pediatric Cancer: Q&A With John Maris, MD

Published on
Oct 23, 2018
in Cornerstone Blog
Photo of John Maris, MD
Unique resource will turbocharge scientists' efforts to identify and prioritize which new drugs to take to clinical trials.
1 - 10 of 20

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In this section

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  • Novel Therapeutics for Bleeding Disorders (1)
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  • Tasian Laboratory (1)

In this section

Filter By

  • Principal Investigator / Faculty (2)

Organizations

  • Cancer Immunotherapy (CAR-T) (5)
  • Division of Oncology (5)
  • Center for Childhood Cancer Research (3)
  • Division of Cancer Pathobiology (3)
  • Department of Pediatrics (2)
  • PolicyLab (2)
  • Thomas-Tikhonenko Laboratory (2)
  • Center for Applied Genomics (1)
  • Center for Autism Research (1)
  • Center for Computational and Genomic Medicine (1)
  • Clinical In Vivo Gene Therapy (1)
  • Department of Pathology and Laboratory Medicine (1)
  • Department of Radiology (1)
  • Division of Allergy and Immunology (1)
  • Division of Cardiology (1)
  • Division of Hematology (1)
  • Division of Infectious Diseases (1)
  • Jolley Laboratory (1)
  • Mir Laboratory (1)
  • Novel Therapeutics for Bleeding Disorders (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Tasian Laboratory (1)
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