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Results for Bone Marrow Failure

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Timothy S. Olson, MD, PhD
Timothy S. Olson Headshot

Dr. Olson aims to improve diagnostics and treatment of bone marrow failure (BMF) syndromes, and to improve clinical hematopoietic stem cell transplantation (HSCT) outcomes. He conducts clinical trials of HSCT for non-malignant hematologic diseases. His laboratory explores both basic and translational research focused on genomics of BMF and the impact of BMF on hematopoietic niche function during HSCT.

E-mail:
olsont [at] chop.edu
Peter Kurre, MD
Peter Kurre

Dr. Kurre's laboratory has longstanding expertise in Fanconi Anemia (FA), a genetic condition with prominent hematologic complications. With training in transplantation and hematopoietic stem cell biology, he hopes to improve the understanding of the progressive hematopoietic failure in patients with bone marrow failure and FA, broaden diagnostic approaches, and develop next generation therapies.

E-mail:
kurrep [at] chop.edu
Julia T. Warren, MD, PhD
Julia T. Warren

Dr. Warren studies normal and aberrant hematopoiesis, with a special interest in granulopoiesis. Her research aims to understand the pathogenesis of severe congenital neutropenia and its risk for malignant transformation. She has a clinical interest in neutropenia syndromes including clinical trials.

E-mail:
warrenjt [at] chop.edu
Wei Tong, PhD
Wei Tong

Dr. Tong investigates cytokine receptor signaling in normal and neoplastic hematopoietic development. She uses integrated approaches encompassing biochemistry, molecular biology, mouse models, and primary human samples to understand signaling events emanating from cytokine receptors that regulate the development of hematopoietic stem/progenitor cells.

E-mail:
tongw [at] chop.edu
Nancy J. Bunin, MD

Dr. Bunin's current research focuses on the development of hematopoietic stem cell graft engineering for allogeneic transplantation to minimize graft-versus-host disease (GVHD), promote engraftment and immune reconstitution. She has also developed protocols for rapid manufacture of viral cytotoxic T lymphocytes to treat or prevent life threatening viral infections post hematopoietic stem cell transplant.

E-mail:
buninn [at] chop.edu
Narasaiah Kovuru, PhD
Narasaiah Kovuru

Narasaiah Kovuru’s research focuses on understanding the origins of hematopoietic failure/bone marrow failure in Fanconi Anemia working with the murine model.

E-mail:
kovurun [at] chop.edu
Suying Liu, BS
Suying Liu

Suying Liu leads the research project into the clonal restraints of hematopoiesis in an inherited bone marrow failure syndrome, Fanconi Anemia, to promote better understanding and treatment of pediatric hematological disorders.

E-mail:
lius10 [at] chop.edu
Omar A. Banda, PhD
Omar A. Banda

Omar Banda investigates therapeutic applications of novel nanoparticle delivery systems for the treatment of Fanconi Anemia.

E-mail:
bandao [at] chop.edu
Jian Meng Fan
Jian Meng Fan

Jian Meng Fan is a research technician III in Dr. Kurre’s Laboratory.

E-mail:
fanj1 [at] chop.edu

CHOP Researchers Elucidate Mechanism Behind Immunotherapy Resistance in B-ALL

Published on
Jan 24, 2022
in Cornerstone Blog
Researchers Find Mechanism of Treatment Resistance in B-ALL
Researchers identified aberrant splicing as a culprit behind treatment resistance in B-ALL.
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In this section

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  • Principal Investigator / Faculty (5)
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  • Comprehensive Bone Marrow Failure Center (15)
  • Department of Pediatrics (3)
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  • Division of Rheumatology (1)
  • Mitochondrial Medicine (1)

In this section

Filter By

  • Principal Investigator / Faculty (5)
  • Researcher / Lab Personnel (4)

Organizations

  • Comprehensive Bone Marrow Failure Center (15)
  • Department of Pediatrics (3)
  • PolicyLab (3)
  • Center for Injury Research and Prevention (2)
  • Division of Hematology (2)
  • Kurre Laboratory (2)
  • Center for Applied Genomics (1)
  • Center for Autism Research (1)
  • Center for Data-Driven Discovery in Biomedicine (1)
  • Clinical Futures (1)
  • Division of Cancer Pathobiology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Human Genetics (1)
  • Division of Infectious Diseases (1)
  • Division of Neurology (1)
  • Division of Oncology (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Rheumatology (1)
  • Mitochondrial Medicine (1)
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