Dr. Zemel's overall research program aims to improve the understanding of lifelong health and how it relates to childhood antecedents of physical growth and maturation, body composition, population ancestry/genetics, and lifestyle factors. Such insight has practical implications for disease prevention and lifelong wellness, as well as broader scientific implications for understanding human plasticity and evolution.
Dr. Mitchell's research aims to explain variations in childhood growth patterns related to the causes and prevention of diseases in later life. This includes studying the impact of behaviors and genes on body composition during development, especially childhood sleep and physical activity behavior.
Bone mineral accrual doesn't keep pace with height growth prior to adolescence, according to a national study. After a teenager reaches adult height, bone mineral accrual tends to play catch-up: Roughly 10 percent of bone mass continues to accumulate after height growth is complete. The study findings also suggest that bone growth is site-specific, with bone mineral density developing at different rates in different parts of the skeleton.
CAR T-cell therapy tops this week's research roundup, with news about the experimental immunotherapy designed to re-engineer a patient's cells to fight cancer making late-breaking and captivating headlines across the nation.
Whether children are under the steady hand of surgeon and anesthesiologist, or medical and research trainees are under the guidance of an experienced mentor, knowledge makes all the difference. This much is clear from the top stories in our weekly roundup of research news at The Children's Hospital of Philadelphia.
Our news highlights this week include new evidence-based sleep recommendations; a new champion for helping military families navigate children’s healthcare issues; a lifesaving solution to a mysterious surgical side effect; and an encouraging finding to help children predisposed to fragile bones grow up stronger.