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Results for Biliary Atresia

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Nancy B. Spinner, PhD
Nancy B. Spinner

Dr. Spinner's research focuses on the etiology and expressivity of pediatric developmental disorders. She uses genomic methods to focus on the multisystem disorder Alagille syndrome and biliary atresia, a likely heterogeneous and poorly understood condition. She is also interested in using genomic tools to continue to improve diagnostic rates for constitutional genetic disorders.

E-mail:
spinner [at] chop.edu
Kathleen Loomes, MD
Kathleen Loomes

Dr. Loomes' research is focused on clinical and translational studies in pediatric liver disease. She works with National Institutes of Health-funded national consortia to conduct studies investigating the etiology and treatment for rare pediatric liver diseases including biliary atresia, Alagille syndrome, and others. Dr. Loomes also collaborates with other investigators at Children’s Hospital of Philadelphia to investigate genetic causes of pediatric liver disease.

E-mail:
loomes [at] chop.edu
Elizabeth B. Rand, MD
Elizabeth B. Rand

Dr. Rand's research interests include clinical studies of biliary atresia and studies of immunization, immune suppression, and long-term outcome after transplantation. Her basic science interests in liver development and fibrosis are carried out as collaborations with scientists who utilize the liver tissue bank.

E-mail:
rand [at] chop.edu
Alan W. Flake, MD
Alan W. Flake

Dr. Flake is a general pediatric surgeon with a clinical and research focus on prenatal treatment ranging from the fetal surgical repair of anatomic anomalies to prenatal stem cell and gene therapy. He has extensive experience in developing rodent, canine, and sheep models for in utero transplantation and for investigating fetal surgery for anatomic malformations.

E-mail:
flake [at] chop.edu

CHOP Honors Distinguished Research Trainees on Poster Day

Published on
Mar 1, 2016
in Cornerstone Blog
Poster Day at The Children’s Hospital of Philadelphia Research Institute is a tradition now in its 26th year. At this event, trainee-level researchers come together to present poster summaries of their work with the CHOP community.

Genetic Study Offers Clues About Rare Liver Disease Biliary Atresia

Published on
Apr 25, 2013
in Cornerstone Blog
A new genetic study may shed light on the causes of the rare childhood disease biliary atresia. The leading cause of liver transplantation in children, biliary atresia (BA) is a rare, life-threatening condition in which the ducts that carry bile from the liver to the gallbladder become blocked.

Spinner Laboratory

Spinner Lab

Research in the Spinner Lab focuses understanding the etiology and expressivity of pediatric developmental disorders. The lab uses genomic methods to focus on the multisystem disorder Alagille syndrome and biliary atresia, a likely heterogeneous and poorly understood condition.

Metabolism, Nutrition, and Physical Development Research Affinity Group

Baby Boy

Investigating the causes and consequences of metabolic and nutritional disorders to identify disease prevention and treatment strategies.

Fred and Suzanne Biesecker Pediatric Liver Center

Fred and Suzanne Biesecker Pediatric Liver CenterFred and Suzanne Biesecker Pediatric Liver Center

Researching the causes of liver diseases and new ways to treat children with these disorders using a bench-to-bedside approach that integrates clinical care, clinical research, and basic science research.

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In this section

Filter By

  • Principal Investigator / Faculty (4)

Organizations

  • Center for Applied Genomics (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Fred and Suzanne Biesecker Pediatric Liver Center (1)
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