Results for Autoimmune Lymphoproliferative Syndrome

1 - 5 of 5

Dr. Grupp develops and conducts preclinical testing of engineered cell therapies and signal transduction inhibitors in leukemia, in pediatric immunotherapy trials, and in the manufacture and use of cellular therapeutics in preclinical, good manufacturing practices, and clinical trial settings. Dr. Grupp leads most CTL019 (CD19 CAR) clinical trials, and his colleagues are the global leaders in highly active CAR T cell therapy.

E-mail:

grupp [at] chop.edu

David T. Teachey, MD

Dr. Teachey's research focuses on investigating novel therapeutics for children with white blood cell diseases, including ALL and a rare autoimmune disease called Autoimmune Lymphoproliferative Syndrome (ALPS). His research in ALL focuses on studying leukemic cells from children with high-risk disease.

E-mail:

teacheyd [at] chop.edu

Drug Trial Shows "Profound" Success Treating Rare Blood Disorders

Published on

Nov 3, 2015

in Cornerstone Blog

When the immune system inappropriately destroys blood cells, in a relatively rare group of diseases called autoimmune cytopenias, children may suffer for years with anemia, uncontrolled bleeding, and vulnerability to infections, while their parents struggle to find a diagnosis.

Groundbreaking Leukemia Research Featured at ASH Annual Meeting

Published on

Dec 9, 2013

in Cornerstone Blog

The Children's Hospital of Philadelphia's groundbreaking leukemia research was on display at the recent American Society of Hematology (ASH) Annual Meeting. Held in New Orleans, the ASH Annual Meeting brought together approximately 20,000 researchers, clinicians, and industry representatives, with data from more than 5,300 abstracts presented.

Teachey Laboratory

The Teachey Lab studies perturbations in leukemic cell signal transduction pathways with the aim of identifying targeted cancer inhibitors and immunotherapies that can treat children with high-risk leukemias and autoimmune lymphoproliferative syndrome.