Results for Animal Models

Dr. Smith is a laboratory animal medicine veterinarian. As Technical Director of the CCMT Comparative Medicine Services Core, he helps guide promising therapeutics and devices from discovery and developmental studies through nonclinical studies.

Dr. Cahill's focuses on improving treatments for patients with early onset chest and spinal deformity, employing a combination of clinical, biomechanical, and basic science research approaches.

Dr. Bhatnagar's research aims to further the understanding of the neural basis of individual differences in response to stressful experiences. This includes identifying neural substrates that produce resiliency or vulnerability to the effects of stress and determining treatments to mitigate vulnerability and to promote resiliency through both preclinical and translational studies.

Dr. Ghanem investigates the impact of transcriptional gene expression controls and mRNA processing upon the severity and progression of pediatric inflammatory bowel disease.

Dr. Lynch maintains a dynamic program that involves clinical, translational, and basic science research efforts focused on the rare disease Friedreich ataxia.

Dr. Shih studies the metabolic interplay between cell types within the neurovascular unit during stroke to develop effective, novel mitochondrial-directed therapeutics to improve post-stroke disability. She works with small and large animal models of childhood arterial ischemic stroke.

Dr. Flake is a general pediatric surgeon with a clinical and research focus on prenatal treatment ranging from the fetal surgical repair of anatomic anomalies to prenatal stem cell and gene therapy. He has extensive experience in developing rodent, canine, and sheep models for in utero transplantation and for investigating fetal surgery for anatomic malformations.

Dr. Margaritis uses biochemical, molecular, and complex in vivo methodology within the field of coagulation to advance the understanding of molecular mechanisms involved in pro- and anti-coagulant reactions, and translate research for the treatment of coagulation defects.

Dr. Davidson works to understand the molecular basis of childhood onset neurodegenerative diseases and the development of gene and small molecule therapies for treatment. She also focuses on how noncoding RNAs participate in neural development and neurodegenerative disease processes, and how they can be harnessed for therapies.

Dr. Sutton is an internationally recognized expert in pediatric cardiac arrest. His career focus is on developing and evaluating novel techniques and devices to improve the care delivered during in-hospital resuscitation attempts.