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Justine Shults, PhD, MS
Justine Shults

Dr. Shults works to develop statistical methods for longitudinal data that include semi-parametric approaches to account for subject/cluster level associations and maximum likelihood-based approaches for simulation and analysis of discrete longitudinal outcomes that may have overdispersion.

E-mail:
shultsj [at] chop.edu
Marni J. Falk, MD
Marni J. Falk

Dr. Falk is a Clinical Geneticist who serves as executive director of the Mitochondrial Medicine Frontier Program. Her translational research lab investigates the causes and global metabolic consequences of mitochondrial disease, as well as targeted therapies, in C. elegans, zebrafish, mouse, and human tissue models of genetic-based respiratory chain dysfunction.

E-mail:
falkm [at] chop.edu
Jarcy Zee, PhD
Jarcy Zee

Dr. Zee's statistical methods research includes topics in survival analysis, measurement error, observational data methods, and machine learning. Her clinical research is focused on kidney disease, specifically in clinical and pathology markers of glomerular and chronic kidney disease progression.

E-mail:
zeej [at] chop.edu
Stephan Kadauke, MD, PhD
Stephan Kadauke

Dr. Kadauke is the associate director of the Cell and Gene Therapy Laboratory at CHOP and the medical director of the Cell and Gene Therapy Informatics team. His research focuses on developing novel ways to manufacture cell therapies with the goal of accelerating and broadening patient access to these life-saving therapies.

E-mail:
kadaukes [at] chop.edu
Di Shu, PhD
Di Shu, PhD

Dr. Shu's research focuses on developing and applying suitable statistical methods for assessing comparative safety and effectiveness of medical products.

E-mail:
shud [at] chop.edu
Christopher B. Forrest, MD, PhD
Christopher B. Forrest Headshot

Dr. Forrest's research focuses on developing novel ways of conducting multi-center pediatric applied clinical research, child health services and outcomes research, pediatric person-reported outcome measure development and application, life course health science, learning health systems science, and policies and programs that promote the lifelong health of children. He has a particular interest in the concept and measurement of health.

E-mail:
forrestc [at] chop.edu
Christopher J. Cardinale, MD, PhD
Christopher J. Cardinale

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:
cardinalec [at] chop.edu
Kai Tan, PhD
Kai Tan

Dr. Tan studies transcriptional regulation during normal development and disease. This involves the interplay of multiple transcription and epigenetic factors in a 3D chromosomal environment. Using experimental genomics and computational modeling, Dr. Tan investigates transcriptional regulatory networks underlying embryonic hematopoiesis, T cell differentiation, and pediatric leukemia.

E-mail:
tank1 [at] chop.edu

In the News: ASCI Membership, STAT Madness, Brain Chart, Single Ventricle Research Fund

Published on
Mar 3, 2023
in Cornerstone Blog
In the News: ASCI Membership, STAT Madness, Brain Chart
In this news roundup, learn about the achievements of CHOP researchers from societal inductions to grant- and grand-prize recipients.

Snapshot Science: Does Serotonin Contribute to Heart Valve Disease Progression in Patients With Low Serotonin Transport Activity?

Published on
Feb 13, 2023
in Cornerstone Blog
Does Serotonin Contribute to Heart Valve Disease Progression in Patients With Low Serotonin Transport Activity?
Researchers explore how serotonin may affect the heart’s mitral valve and potentially accelerate degenerative mitral regurgitation.
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In this section

Filter By

  • Principal Investigator / Faculty (8)

Organizations

  • Department of Biomedical and Health Informatics (12)
  • Department of Pediatrics (8)
  • PolicyLab (8)
  • Division of Human Genetics (7)
  • Center for Data-Driven Discovery in Biomedicine (6)
  • Department of Pathology and Laboratory Medicine (6)
  • Center for Applied Genomics (5)
  • Center for Autism Research (5)
  • Division of Neonatology (5)
  • Center for Computational and Genomic Medicine (4)
  • Center for Injury Research and Prevention (4)
  • Clinical Futures (4)
  • Division of Allergy and Immunology (4)
  • Division of Infectious Diseases (4)
  • Center for Childhood Cancer Research (3)
  • Division of Cardiology (3)
  • Division of Gastroenterology, Hepatology, and Nutrition (3)
  • Division of Neurology (3)
  • Division of Oncology (3)
  • Mitochondrial Medicine (3)
  • Center for Child Injury Prevention Studies (2)
  • Center for Pediatric Heart Valve Disorders (2)
  • Children’s Oncology Group (2)
  • Department of Surgery (2)
  • Division of Pulmonary and Sleep Medicine (2)
  • Division of Urology (2)
  • Institutional Review Board (2)
  • Lifespan Brain Institute (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Beckwith-Wiedemann Syndrome Program of Excellence (1)
  • Bhoj Laboratory (1)
  • Brain-Gene-Development Lab (1)
  • Center for Applied Genomics Laboratory (1)
  • Center for Mitochondrial and Epigenomic Medicine (1)
  • Center for Spatial and Functional Genomics (1)
  • CHOP Cardiovascular Institute (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Computational Epigenetics (1)
  • Department of Anesthesiology and Critical Care Medicine (1)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (1)
  • Department of Radiology (1)
  • Division of Adolescent Medicine (1)
  • Division of Emergency Medicine (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Hematology (1)
  • Division of Nephrology (1)
  • Division of Neurosurgery (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Protective Immunity (1)
  • eMERGE (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Feudtner Laboratory (1)
  • FVRx + Home Plate (1)
  • Minds Matter Concussion Program (1)
  • Mitchell Laboratory (1)
  • Office of Academic Training and Outreach Programs (1)
  • Pei Laboratory (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Romberg Laboratory (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)
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