About PKIDS Care Improvement Network

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The rapid increase in the prevalence of kidney stones among youth has resulted in a large population of patients for whom little evidence exists to guide clinical care. Our research arose from patients’ expressed need to better understand the effectiveness of different surgical approaches to remove kidney stones, the impact of these surgeries on their lives, and how long it takes to recover. To address this critical knowledge gap, we have formed the Pediatric KIDney Stone (PKIDS) Care Improvement Network, which is a community of patients, caregivers, and clinicians who perform collaborative studies of kidney stones at over 25 pediatric healthcare systems in North America.

The overall objective of Pediatric KIDney Stone (PKIDS) Care Improvement Network research study is to compare stone clearance and patients’ experiences for the three existing surgical treatments to remove stones: ureteroscopy (URS), shockwave lithotripsy (SWL), and percutaneous nephrolithotomy (PCNL).

Our primary objective is to compare stone clearance for URS, SWL, and PCNL using a standardized ultrasound protocol to assess stone clearance. Our secondary objective is to compare patients’ experiences after URS, SWL, and PCNL in the immediate (one-week) and delayed (three-week, six-week, and three-month) post-operative period by assessing pain interference, anxiety, psychological stress, peer relationships, family relationships, and urinary symptoms.

This study will take approximately three years to complete. Children and young adults ages 8-21 years of age will be eligible to participate. This study is currently recruiting. It is funded by the Patient-Centered Outcomes Research Institute.

The results of this study will improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and will enable urologists to use techniques that result in the best outcomes for these surgeries.

Study Sites

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