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Dr. Chou investigates the mechanisms of normal hematopoietic development and how these become disrupted in hematologic diseases.
Dr. Chou's research laboratory investigates the mechanisms of normal hematopoietic development and how these become disrupted in hematologic diseases. Her laboratory primarily uses induced pluripotent stem cells and primary human cells to model blood diseases and study their underlying pathophysiology. They specifically focus on erythro-megakaryocytic development and the role of genetic modifiers in anemia, thrombocytopenia, and myeloproliferative disorders.
Dr. Chou's other research focus is alloimmunization in patients with sickle cell disease. Her research has demonstrated that transfusion of patients with sickle cell disease using African American donor units and antigen matched for D, C, E, and K did not reduce Rh alloimmunization and many Rh antibodies were explained by inheritance of variant RH genes.
Her current work focuses on alloimmunization prevention and transfusion safety for patients with sickle cell disease using genomics to identify risk of alloantibody formation and selecting compatible blood donors.
Education and Training
BA, Duke University (History), 1995
MD, New York Medical College, 2000
Fellowship, Children's Hospital of Philadelphia (Hematology/Oncology), 2006
Fellowship, Hospital of the University of Pennsylvania (Transfusion Medicine), 2010
Titles and Academic Titles
Associate Professor of Pediatrics
American Society of Hematology, 2004-
American Society of Pediatric Hematology/Oncology, 2005-
American Association of Blood Banks, 2008-
The American Society of Clinical Oncology Young Investigator Award, 2006
The Hope Street Kids Foundation Grant Award Fellow Award, 2006
The Leukemia and Lymphoma Society Fellow Award, 2006
National Blood Foundation Young Investigator Scholarship, 2011
National Blood Foundation Hall of Fame, 2018