Dr. Canna has led an independent translational research program since 2017, but has been dedicated to leveraging genetic and clinical insights to improve mechanistic understanding and outcomes for patients with immune dysregulation diseases since 2005. His group has made foundational contributions to the fields of inflammasome and cytokine biology, with translational impacts related to measuring and manipulating cytokines like Interleukin-18 in diseases like macrophage activation syndrome. He led teams at the NIAMS Intramural Research Program and University of Pittsburgh before being recruited back to the University of Pennsylvania and Children's Hospital of Philadelphia in 2021 to help expand the clinical and research potential of the CHOP Immune Dysregulation program.

MD, George Washington University, Washington, DC

NIH Clinical Research Training Program (CRTP)

Residency, University of Colorado, Colorado Children’s Hospital, Denver (Pediatrics)

Fellowship, University of Pennsylvania, Children’s Hospital of Philadelphia (Pediatric Rheumatology)

Post-doctoral Fellowship: NIAMS Metzger Scholar in Translational Research

Board Certification, American Board of Pediatrics (Pediatric Rheumatology)

Attending Physician, Rheumatology and Immune Dysregulation

Associate Professor of Pediatrics

Histiocyte Society, HLH Steering Committee Chair (2023-present)

International Cytokine and Interferon Society, 2019-

American College of Rheumatology, 2009-

American Association of Immunologists

Clinical Immunology Society

International Society for Systemic Autoinflammatory Diseases

Histocyte Society, 2013-

Childhood Arthritis and Rheumatology Research Alliance, 2010-

Lady Barbara Colyton Prize for Research in Autoimmunity, 2023

Elected Member, Henry Kunkel Society, 2020

Associazione Italiana Linfoistiocitosi Emofagocitica Ricciardi Award, 2020

Elected Member, Society for Pediatric Research, 2019

American Society of Clinical Investigation Young Physician-Scientist Award, 2018

American Society of Clinical Investigation Young Physician-Scientist Outstanding Poster Award, 2018

American College of Rheumatology Research Foundation Pediatric Rheumatology Research Award, 2012

American College of Rheumatology Distinguished Fellow Award, 2012

Children's Hospital of Philadelphia, Sani Family Foundation, Rheumatology Fellow Award, 2010