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Michael A. Levine, MD, FAAP, FACP, MACE
Michael A. Levine
Medical Director, Center for Bone Health

Dr. Levine has an active laboratory research program that complements and extends his clinical studies. He has identified the molecular basis of several inherited disorders of mineral metabolism. His research interests extend to the molecular basis for embryological development of the parathyroid glands.



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Dr. Levine leads the Center for Bone Health at CHOP, which provides clinical services and access to clinical research studies to children and adolescents with nutritional, metabolic, and genetic disorders of bone and mineral metabolism.

Among his current research projects, Dr. Levine is conducting clinical trials to assess the efficacy and safety of recombinant human parathyroid hormone in adults with hypothyroidism; the efficacy and safety of palovarotene in children with multiple osteochondromatosis; and the safety and efficacy of repurposing rifampin as an inducer of CYP3A4 in patients with hypercalcemia and/or hypercalciuria due to genetic mutations in CYP24A1.

In addition, he is working to identify novel genetic forms of vitamin D-dependent rickets as well as novel genetic disorders of parathyroid function.

Education and Training

AB, Rutgers College (Bacteriology), 1972

MD, Drexel University College of Medicine, 1976

Fellowship, NIH-NIDDK (Endocrinology and Genetics), 1982

Titles and Academic Titles

Medical Director, Center for Bone Health

Chief Emeritus, Division of Endocrinology and Diabetes

Lester Baker Endowed Chair in Pediatric Diabetes

Attending Physician

Professor of Pediatrics and Medicine

Professional Memberships

American Society for Clinical Investigation, 1990-

Association of American Physicians, 2003-

American Pediatric Society, 2007-

Professional Awards

March of Dimes Basil O'Connor Research Scholar, 1982

Fuller Albright Award, American Society for Bone and Mineral Research, 1990

Young Investigator Award, American Federation for Clinical Research, 1992

Progressive Osseous Heteroplasia Association Research Award, 2000

Distinction in Clinical Endocrinology Award, American College of Endocrinology, 2003

Distinction in Parathyroid Research Award, Hypoparathyroidism Association, 2012

Master of the American College of Endocrinology (MACE), 2015

Distinguished Alumnus Research Award, Drexel University College of Medicine, 2015

Frederic C. Bartter Award in Clinical Investigation, American Society for Bone and Mineral Research, 2018

Publication Highlights