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Matthew A. Jolley, MD
Matthew A. Jolley, MD
Assistant Professor

Dr. Jolley's research lab is focused on visualizing and quantifying congenitally abnormal heart structures using 3D imaging with the driving goal of informing surgical and interventional planning in children and adults with congenital heart disease.



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Dr. Matthew Jolley's research lab is focused on the visualization and quantification of congenitally abnormal heart structures using 3D imaging. Children with congenital heart disease have a broad range of anatomy, and there are few readily available commercial tools to facilitate image-based structural phenotyping and patient-specific planning of interventions. As such, his team develops and applies custom tools built upon open-source platforms to help answer critical questions in this unique population.

Dr. Jolley's lab collaborates with cardiac surgeons, cardiac imagers, interventional cardiologists, engineers, and computer scientists with the long-term goal of delivering personalized structural modeling to inform optimal interventions in an individual patient.

Clinically, Dr. Jolley is an attending physician in both pediatric cardiac anesthesia and cardiology (echocardiography). He is a core member of the 3D Echocardiography Group and the Pediatric Valve Center. Dr. Jolley joined CHOP in 2015.

Education and Training

BS, Stanford (Chemistry), 1998

MD, University of Washington, 2003

Pediatric Residency, Boston Children's Hospital, 2006

Engineering Research Fellow, Boston Children's Hospital, 2008

Anesthesia Residency, Stanford University, 2011

Pediatric Cardiology and Pediatric Cardiac Anesthesia, Boston Children's Hospital, 2014

Pediatric Anesthesia, Boston, Children's Hospital, 2015

Titles and Academic Titles

Assistant Professor, Perelman School of Medicine at the University of Pennsylvania

Attending Physician, Pediatric Cardiac Anesthesia

Attending Physician, Pediatric Cardiology (Echo Lab)

Professional Memberships

Society for Pediatric Anesthesia, 2014 -

Society for Cardiac Anesthesia, 2014 -

American Society of Anesthesiologists, 2008 -

Professional Awards

Fellow Teaching Award, Department of Anesthesiology, Children’s Hospital of Philadelphia, 2016

Vonn L. Meyer Travel Award, Boston Children’s Hospital, 2014

Vonn L. Meyer Travel Award, Boston Children’s Hospital, 2013

Frank Sarnquist “Team Player” Award, Stanford University Department of Anesthesia, 2011

California Society of Anesthesiologists Resident Research Award, Second Place, 2011

Western Anesthesia Resident Research Conference, First Place, 2011

California Society of Anesthesiologists Resident Research Award, Third Place, 2009

Western Anesthesia Resident Research Conference, Second Place, 2009

Lovejoy Award, Department of Pediatrics, Boston Children’s Hospital, 2006

Publication Highlights

Sadhwani A, Cheng H, Stopp C, Rollins CK, Jolley MA, Dunbar-Masterson C, Wypij D, Newburger J, Ware J, Thiagarajan RR. Early Neurodevelopmental Outcomes in Children Supported with ECMO for Cardiac Indications.. Pediatr Cardiol. 2020 Feb; 40(5):1072-1083. PubMed PMID: 31079193
Giacalone G, Yamamoto T, Belva F, Hayashi A, Dori Y, Zviman MM, Gysen M, Nam HH, Jolley MA, Kato M. The Application of Virtual Reality for Preoperative Planning of Lymphovenous Anastomosis in a Patient with a Complex Lymphatic Malformation. J Clin Med. 2019 Jan; 8(3). PubMed PMID: 30884770
Ginty OK, Moore JT, Eskandari M, Carnahan P, Lasso A, Jolley MA, Monaghan M, Peters TM. Dynamic, patient-specific mitral valve modelling for planning transcatheter repairs.. Int J Comput Assist Radiol Surg. 2019 Jan; 14(7):1227-1235. PubMed PMID: 31115756
Carnahan P, Ginty O, Moore J, Lasso A, Jolley MA, Herz C, Eskandari M, Bainbridge D, Peters T. Interactive-Automatic Segmentation and Modelling of the Mitral Valve. In: Coudière Y., Ozenne V., Vigmond E., Zemzemi N. (eds). Functional Imaging and Modeling of the Heart. Lecture Notes in Computer Science. 2019 Jan; Springer, Cham. DOI: 10.1007/978-3-030-21949-9_43
Nguyen AV, Lasso A, Nam HH, Faerber J, Aly AH, Pouch AM, Scanlan AB, McGowan FX, Mercer-Rosa L, Cohen MS, Simpson J, Fichtinger G, Jolley MA. Dynamic Three-Dimensional Geometry of the Tricuspid Valve Annulus in Hypoplastic Left Heart Syndrome with a Fontan Circulation. Journal of the American Society of Echocardiography: official publication of the American Society of Echocardiography. 2019 Jan; 32(5):655-666. PubMed PMID: 30826226

Active Grants/Contracts

Current Grants

Computer Modeling of the Tricuspid Valve in Hypoplastic Left Heart Syndrome
NIH 1R01HL153166-01

Pediatric Valve Center
Children's Hospital of Philadelphia Frontier Grant

Cardiac Center Innovation Award
Quantitative 3D Analysis of Inform Systemic Semilunar Valve (SSV) Repair in Children

Cardiac Center Grant
Development and Application of a 3D Toolkit for Procedural Planning of PDA Stent Placement

Recently Completed Grants

Pediatric Heart Network Scholars Award
Computer Modeling of the Complete Atrioventricular Canal Valve in Down Syndrome

Computer-Aided Decision Support System for Catheter-Based Pulmonary Valve Replacement
NIH 1R43HL147747-01A1