In This Section

raffini [at]
Location - People View
11th floor, Room 11022

3501 Civic Center Blvd
Philadelphia, PA 19104
United States

Research Topics
Leslie J. Raffini, MD, MSCE
Leslie J. Raffini, MD, MSCE
Director, Hemostasis and Thrombosis Center

Dr. Raffini's clinical research includes evidence-based strategies to prevent thrombosis in hospitalized children, optimizing anticoagulation therapy to improve outcomes in children with thrombosis, and use of novel therapies in pediatric patients with bleeding disorders.



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Education and Training

BS, University of Wisconsin (Molecular Biology), 1991

MD, University of Wisconsin, 1996

MS, University of Pennsylvania (Clinical Epidemiology), 2005

Titles and Academic Titles

Director, Hemostasis and Thrombosis Center

Associate Professor of Pediatrics

Publication Highlights

Goldenberg NA, Sochet A, Albisetti M, Biss T, Bonduel M, Jaffray J, MacLaren G, Monagle P, O'Brien S, Raffini L, Revel-Vilk S, Sirachainan N, Williams S, Zia A, Male C; Pediatric/Neonatal Hemostasis and Thrombosis Subcommittee of the ISTH SSC. Consensus-based clinical recommendations and research priorities for anticoagulant thromboprophylaxis in children hospitalized for COVID-19-related illness. J Thromb Haemost. 2020 Nov; 18(11): 3099-3105. PubMed PMID: 33174388
McCary I, Guelcher C, Kuhn J, Butler R, Massey G, Guerrera MF, Ballester L, Raffini L. Real-world use of emicizumab in patients with haemophilia A: Bleeding outcomes and surgical procedures. Haemophilia. 2020 Jul; 26(4):631-636. doi: 10.1111/hae.14005. Epub 2020 Apr 20. PMID: 32311809.
Witmer C, Raffini L. Treatment of venous thromboembolism in pediatric patients. Blood. 2020 Jan; 135(5): 335-343. PubMed PMID: 31917400
Monagle P, Cuello CA, Augustine C, Bonduel M, Brandão LR, Capman T, Chan AKC, Hanson S, Male C, Meerpohl J, Newall F, O'Brien SH, Raffini L, van Ommen H, Wiernikowski J, Williams S, Bhatt M, Riva JJ, Roldan Y, Schwab N, Mustafa RA, Vesely SK. American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism. Blood Adv. 2018 Nov; 2(22): 3292-3316. PubMed PMID: 30482766
Kamdar A, Rintoul N, Raffini L. Anticoagulation in neonatal ECMO. Semin Perinatol. 2018 Mar; 42(2): 122-128. PubMed PMID: 29336832