Ph.D., D.D.S.
The Children's Hospital of Philadelphia Translational Research Program in Pediatric Orthopaedics Division of Orthopaedic Surgery Department of Surgery 3615 Civic Center Boulevard Abramson Research Center 910B
Research Associate Professor of Orthopaedic Surgery at University of Pennsylvania School of Medicine (2012– present)
PhD, Developmental Biology, Okayama University (1992)
D.D.S., Matsumoto Dental University (1985)
Selected Publications
Laurita Jason, Koyama Eiki, Chin Bianca, Taylor Jesse A, Lakin Gregory E, Hankenson Kurt D, Bartlett Scott P, Nah Hyun-Duck. The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses.. Developmental dynamics : an official publication of the American Association of Anatomists. Vol 240(11) . 2011 Nov:2584-96.
Zhang Xianrong, Siclari Valerie A, Lan Shenghui, Zhu Ji, Koyama Eiki, Dupuis Holly L, Enomoto-Iwamoto Motomi, Beier Frank, Qin Ling. The critical role of the epidermal growth factor receptor in endochondral ossification.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Vol 26(11) . 2011 Nov:2622-33.
Kinumatsu T, Shibukawa Y, Yasuda T, Nagayama M, Yamada S, Serra R, Pacifici M, Koyama E. TMJ development and growth require primary cilia function.. Journal of dental research. Vol 90(8) . 2011 Aug:988-94.
Zak Beverly M, Schuksz Manuela, Koyama Eiki, Mundy Christina, Wells Dan E, Yamaguchi Yu, Pacifici Maurizio, Esko Jeffrey D. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.. Bone. Vol 48(5) . 2011 May:979-87.
Sugito H, Shibukawa Y, Kinumatsu T, Yasuda T, Nagayama M, Yamada S, Minugh-Purvis N, Pacifici M, Koyama E. Ihh signaling regulates mandibular symphysis development and growth.. Journal of dental research. Vol 90(5) . 2011 May:625-31.
Mundy Christina, Yasuda Tadashi, Kinumatsu Takashi, Yamaguchi Yu, Iwamoto Masahiro, Enomoto-Iwamoto Motomi, Koyama Eiki, Pacifici Maurizio. Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine.. Developmental biology. Vol 351(1) . 2011 Mar:70-81.
Koyama Eiki, Yasuda Tadashi, Minugh-Purvis Nancy, Kinumatsu Takashi, Yallowitz Alisha R, Wellik Deneen M, Pacifici Maurizio. Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.. Development (Cambridge, England). Vol 137(22) . 2010 Nov:3795-800.
Yasuda T, Mundy C, Kinumatsu T, Shibukawa Y, Shibutani T, Grobe K, Minugh-Purvis N, Pacifici M, Koyama E. Sulfotransferase Ndst1 is needed for mandibular and TMJ development.. Journal of dental research. Vol 89(10) . 2010 Oct:1111-6.
Ochiai T, Shibukawa Y, Nagayama M, Mundy C, Yasuda T, Okabe T, Shimono K, Kanyama M, Hasegawa H, Maeda Y, Lanske B, Pacifici M, Koyama E. Indian hedgehog roles in post-natal TMJ development and organization.. Journal of dental research. Vol 89(4) . 2010 Apr:349-54.
Koyama Eiki, Yasuda Tadashi, Wellik Deneen M, Pacifici Maurizio. Hox11 paralogous genes are required for formation of wrist and ankle joints and articular surface organization.. Annals of the New York Academy of Sciences. Vol 1192. 2010 Mar:307-16.