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Dr. Raffini's clinical research includes evidence-based strategies to prevent thrombosis in hospitalized children, optimizing anticoagulation therapy to improve outcomes in children with thrombosis, and use of novel therapies in pediatric patients with bleeding disorders.
Dr. Rand's research interests include clinical studies of biliary atresia and studies of immunization, immune suppression, and long-term outcome after transplantation. Her basic science interests in liver development and fibrosis are carried out as collaborations with scientists who utilize the liver tissue bank.
Dr. Rasooly's research aims to understand diagnostic decision making and leverage the electronic health record to support diagnostic excellence. Her current work focuses on recognition of child abuse, evaluating decision making in simulation, and improving diagnostic performance at CHOP.
Dr. Rempell is active in research evaluating the role of bedside ultrasound in the care of patients in the Emergency Department, as well as projects evaluating the efficacy of educational interventions to instruct attendings and residents about bedside ultrasound.
Dr. Renjilian is a pediatrician who specializes in adolescent medicine and sports medicine. His research interests and work include understanding how sports and physically active recreation can help young people to develop resilience.
Dr. Resnick's research focuses on the cell signaling mechanisms of oncogenesis and tumor progression in brain tumors. He studies signaling cascades and alterations to elucidate the molecular and genetic underpinnings in order to develop targeted therapies. As co-director of the Center of Data-Driven Discovery in Biomedicine, he leads a multidisciplinary team building and supporting a scalable, patient-focused healthcare and educational discovery ecosystem.
Dr. Rheingold's research interests center on acute lymphocytic leukemia, and she serves on the Children's Oncology Group's Relapsed ALL, Infant ALL, and Complementary Therapies committees. In addition, she is investigates complementary and alternative therapies, supportive care for oncology patients undergoing chemotherapy, medical education, and rare childhood tumors.
Dr. Rivella is an expert in the pathophysiology of erythroid and iron disorders and in the generation of lentiviral vectors for the cure of hemoglobinopathies. He also investigates additional disorders such as anemia of inflammation and hemochromatosis.
The research interests of Dr. Robbins include addressing social determinants of early childhood obesity, disparities in childhood obesity treatment and outcomes, and understanding interventions that address food access to improve child weight status. She is also interested in improving policies relating to food systems and physical activity.
Dr. Roberts investigates brain-wave scanning with magnetoencephalography (MEG) and works to identify biomarkers for neuropsychiatric disorders like autism. Those biomarkers are for diagnosis, prognosis, stratification, and response monitoring as well as substrate identification for targeted therapy. Putting the "bio" into biomarkers is a major emphasis of Dr. Roberts' research, for which he uses advanced diffusion magnetic resonance imaging (MRI) and edited spectroscopy.
Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.
Dr. Rossano's extensive research experience primarily involves the epidemiology and outcomes of cardiovascular disease in children, and multi-institutional collaborative observational and interventional studies. His particular research interests include evaluating the treatment and outcomes of pediatric cardiomyopathy, heart failure, and transplantation.
Dr. Rubenstein's research focuses on basic and translational studies of novel means to improve outcomes in cystic fibrosis. He initially focused on correcting the dysfunction of mutant cystic fibrosis transmembrane conductance regulator (CFTR) proteins, which led him to study how molecular chaperones regulate the biogenesis and trafficking of CFTR and other proteins that are relevant to cystic fibrosis.
Classic food allergies are mediated through immunoglobulin E and manifest as hives, vomiting, and anaphylaxis. Dr. Ruffner investigates the immune mechanisms of food allergy disorders which are not mediated through immunoglobulin E. In particular, the mechanisms of eosinophilic esophagitis and food-protein induced enterocolitis syndrome are of particular interest in Dr. Ruffner's laboratory.
Dr. Ruppel’s research focuses on optimizing the use of technology and data in acute care to improve patient safety and outcomes. She seeks to improve integration of technology and data into clinical workflows and address unintended consequences like alarm fatigue.