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Dr. Pacifici's biomedical research spans three decades and has explored mechanisms of skeletal development and growth in fetal and postnatal life. Specifically, his focus has been on identifying the cellular and molecular mechanisms that regulate the differentiation of progenitor cells and permit assembly of distinct skeletal structures, and on aberrations of these mechanisms in pediatric skeletal disorders.
Dr. Panitch has long had an interest in the care of children with complex respiratory problems and those requiring technology assistance. His research has focused on airway smooth muscle, dynamic airway collapsibility, RSV bronchiolitis pathogenesis and prevention, and barriers to transitioning technology dependent children to adult care.
Dr. Parish-Morris investigates social communication, specifically how vocal communication develops in children and adolescents with autism spectrum disorder. She uses computational approaches and machine learning to identify objective and reliable behavioral markers for use in screening, treatment and intervention response tracking, and to advance biological research.
Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.
Dr. Phillips' research interests involve learning health systems and the intersection of technology and clinical informatics with clinical research for pediatric oncology patients. His current focus is on developing novel automated methods to identify cancer patients with malnutrition and optimizing their nutritional support. He has a secondary interest in quality improvement research for supportive care in pediatric oncology.
In addition to serving as chief of the Division of Gastroenterology, Hepatology, and Nutrition, Dr. Piccoli pursues research about metabolic and genetic liver disease, inflammatory bowel disease, and rare gastrointestinal disorders. He is a member of the group that discovered Jagged1 and NOTCH2 as the primary causes of Alagille syndrome.
Dr. Pinney investigates the molecular mechanisms that link an adverse intrauterine milieu to the development of diabetes and obesity later in life. Specifically, she is researching how intrauterine growth restriction, gestational diabetes and in utero exposure to environmental toxicants contribute to the development of diabetes and obesity in offspring.
Dr. Poncz investigates the megakaryocyte-platelet-thrombus axis. The process by which hematopoietic stem cells differentiate into megakaryocytes are the central foci of his laboratory work. Many of his studies focus on the biology and pathobiology of the platelet-specific proteins, chemokines Platelet Factor 4 (PF4)/Platelet Basic Protein (PBP) and the integrin alphaIIb/beta3 receptor.
Dr. Power's research focuses on the implementation of evidence-based interventions for children with attention-deficit/hyperactivity disorder (ADHD) in community settings, including schools and primary care practices. The emphasis of his work is on developing the capacity of professionals in the community to provide evidence-based care for children and adolescents with attention, behavior, and emotional difficulties.
Dr. Prosser's research focuses are the development and rehabilitation of movement in children, particularly those with neurological impairments. This includes the investigation of the development of impaired movement, the study of novel motor rehabilitation interventions in children, and the interaction between the processes of neuroplasticity and neuromaturation in sensorimotor systems.