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Dr. Kalish's research focuses on understanding the molecular and epigenetic mechanisms that contribute to the predisposition to cancer that is characteristic of pediatric patients with rare imprinted gene disorders, including the overgrowth disorder Beckwith-Wiedemann syndrome (BWS).
Dr. Kassam-Adams’ current research focuses on data sharing and data harmonization in traumatic stress research, and on the development and evaluation of tools that enable trauma-informed and family-centered care in pediatric health settings. Current National Institutes of Health-funded projects include an eHealth tool incorporating game-based screening of child symptoms and functioning, and online training for providers in non-pediatric emergency departments.
Dr. Katz’s investigates the sequelae of obesity and type 2 diabetes mellitus in youth. Her research involves the intersection of sleep, obesity, and glucose intolerance and prevention of cardiovascular risk. Her studies have led to the evaluation of quantitative tools important for assessment of metabolic risk in youth.
Dr. Kelsen’s research focus is on the genetic, immunologic, and microbiomic causes of very early onset inflammatory bowel disease. Through a multidisciplinary team approach, Dr. Kelsen and her colleagues perform genetic sequencing to identify causative genetic variants in children with VEO-IBD, study the function of these variants, and use this information to improve the clinical outcomes for these children.
Dr. Kenyon's research focuses on integrating care systems and reducing outcome disparities for children with asthma. His recent work focuses on developing novel interventions to enhance asthma controller medication use in the highest risk children by leveraging mobile health technology and incentives oriented to the child.
Dr. Keren’s research focuses on the effectiveness and cost-effectiveness of treatments for common problems in general pediatrics, including the prediction and prevention of newborn hyperbilirubinemia (jaundice) and kernicterus (a complication of jaundice), the therapeutic and radiological management of children with urinary tract infections, and the epidemiology and economics of influenza.
Dr. Kersun has a strong interest in trainee education and collaborates with colleagues at Children's Hospital of Philadelphia and other institutions to develop innovative methods of teaching various topics in oncology. She also engages in collaborative research related to the communication of difficult news to patients.
Dr. Kolon is an expert in the care of children with genital disorders and renal/bladder/prostate cancers. His expertise in pediatric urologic oncology includes optimizing organ-sparing surgery and preservation of fertility in oncology patients.
Dr. Koyama's research focuses on Hereditary Multiple Exostoses (HME), a genetic disorder that causes the development of multiple benign tumors on the surface of the metaphyses of long bones. Based on his extensive knowledge of the normal processes of skeletal development and growth, Dr. Koyama's research aims to clarify the molecular mechanisms of HME formation and growth.
Dr. Krantz's lab identifies and characterizes the molecular etiology of syndromic and non-syndromic developmental disorders. He has identified genes for several genetic conditions (Cornelia de Lange Syndrome, CHOPS syndrome, Alagille syndrome, hearing loss) implicating critical molecular pathways in human disorders for the first time. He has been at the forefront of studying the integration of genomics into clinical settings.
Dr. Krishnaswamy studies molecular mechanisms underlying the reactions of blood coagulation. His laboratory investigates how the proteins of blood coagulation interact with each other and with membranes to yield a regulated clotting response to vascular injury or an unregulated response in thrombotic or bleeding disease.
Dr. Kurre's laboratory has longstanding expertise in Fanconi Anemia (FA), a genetic condition with prominent hematologic complications. With training in transplantation and hematopoietic stem cell biology, he hopes to improve the understanding of the progressive hematopoietic failure in patients with bone marrow failure and FA, broaden diagnostic approaches, and develop next generation therapies.
Dr. Kurth is a physician-scientist-leader in pediatric anesthesiology, quality and safety, and pediatric healthcare. He has experience conducting basic, clinical, and translational research studies as well as quality improvement projects to investigate clinical problems and develop technologies to understand the problem and devise therapies to prevent or treat it.